大剂量氧化亚氮吸入引起的神经精神症状1例报告

Tianzhen Chen, Na Zhong, Haifeng Jiang, Min Zhao, Zhikang Chen, Haiming Sun
{"title":"大剂量氧化亚氮吸入引起的神经精神症状1例报告","authors":"Tianzhen Chen,&nbsp;Na Zhong,&nbsp;Haifeng Jiang,&nbsp;Min Zhao,&nbsp;Zhikang Chen,&nbsp;Haiming Sun","doi":"10.11919/j.issn.1002-0829.217084","DOIUrl":null,"url":null,"abstract":"<p><p>Nitrous Oxide, which is also called laughing gas, now ranks as the 7th most popular drug in the world. Nitrous oxide mainly disturbs B12 metabolism and damages nerves, followed by apparent neuropsychiatric symptoms. It's beneficial to the prognosis of patients if we identify and treat their symptoms early. This case report describes a 19-year-old male who presented with auditory hallucination, persecutory delusions and unstable emotions after abuse of nitrous oxide over the course of half a year. Moreover, neurological signs such as weakness and hyperesthesia also appeared. After supplementation of vitamin B12, the neuropsychiatric symptoms improved, while the lower extremities achieved partial recovery. Therapeutically, we should pay attention to nerve repair, motivation enhancement and reinforce interventions that prevent relapse.</p>","PeriodicalId":21886,"journal":{"name":"上海精神医学","volume":"30 1","pages":"56-59"},"PeriodicalIF":0.0000,"publicationDate":"2018-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/8b/sap-30-56.PMC5925601.pdf","citationCount":"17","resultStr":"{\"title\":\"Neuropsychiatric Symptoms Induced by Large Doses of Nitrous Oxide Inhalation: A Case Report.\",\"authors\":\"Tianzhen Chen,&nbsp;Na Zhong,&nbsp;Haifeng Jiang,&nbsp;Min Zhao,&nbsp;Zhikang Chen,&nbsp;Haiming Sun\",\"doi\":\"10.11919/j.issn.1002-0829.217084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nitrous Oxide, which is also called laughing gas, now ranks as the 7th most popular drug in the world. Nitrous oxide mainly disturbs B12 metabolism and damages nerves, followed by apparent neuropsychiatric symptoms. It's beneficial to the prognosis of patients if we identify and treat their symptoms early. This case report describes a 19-year-old male who presented with auditory hallucination, persecutory delusions and unstable emotions after abuse of nitrous oxide over the course of half a year. Moreover, neurological signs such as weakness and hyperesthesia also appeared. After supplementation of vitamin B12, the neuropsychiatric symptoms improved, while the lower extremities achieved partial recovery. Therapeutically, we should pay attention to nerve repair, motivation enhancement and reinforce interventions that prevent relapse.</p>\",\"PeriodicalId\":21886,\"journal\":{\"name\":\"上海精神医学\",\"volume\":\"30 1\",\"pages\":\"56-59\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-02-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/8b/sap-30-56.PMC5925601.pdf\",\"citationCount\":\"17\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"上海精神医学\",\"FirstCategoryId\":\"95\",\"ListUrlMain\":\"https://doi.org/10.11919/j.issn.1002-0829.217084\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"上海精神医学","FirstCategoryId":"95","ListUrlMain":"https://doi.org/10.11919/j.issn.1002-0829.217084","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 17

摘要

一氧化二氮,也被称为笑气,现在是世界上第七大最受欢迎的毒品。氧化亚氮主要干扰B12代谢,损害神经,随后出现明显的神经精神症状。如果我们能及早发现和治疗他们的症状,对病人的预后是有益的。本病例报告描述一名19岁男性,在滥用一氧化二氮半年后出现幻听、受迫害妄想和情绪不稳定。此外,还出现了神经系统症状,如虚弱和感觉亢进。补充维生素B12后,神经精神症状得到改善,下肢部分恢复。在治疗上,我们应该注意神经修复,动机增强和加强干预,防止复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neuropsychiatric Symptoms Induced by Large Doses of Nitrous Oxide Inhalation: A Case Report.

Nitrous Oxide, which is also called laughing gas, now ranks as the 7th most popular drug in the world. Nitrous oxide mainly disturbs B12 metabolism and damages nerves, followed by apparent neuropsychiatric symptoms. It's beneficial to the prognosis of patients if we identify and treat their symptoms early. This case report describes a 19-year-old male who presented with auditory hallucination, persecutory delusions and unstable emotions after abuse of nitrous oxide over the course of half a year. Moreover, neurological signs such as weakness and hyperesthesia also appeared. After supplementation of vitamin B12, the neuropsychiatric symptoms improved, while the lower extremities achieved partial recovery. Therapeutically, we should pay attention to nerve repair, motivation enhancement and reinforce interventions that prevent relapse.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
2341
期刊介绍: Shanghai archives of psychiatry (bimonthly) was founded in 1959 and is sponsored by Shanghai Mental Health Center. The journal is aimed at mental health workers across the country, including psychiatrists and nurses, clinical psychologists, social workers, and people who are committed to the cause of mental health. It focuses on reporting clinical research results and practical experience in the field of psychiatry, and introduces the latest knowledge in psychiatry and related fields. The columns include monographs, case reports, clinical case discussions, reviews, mental health and law, and debates and discussions.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信