{"title":"[根据现行指南,利尿剂在心力衰竭治疗中的地位]。","authors":"Krzysztof Bury, Jadwiga Nessler","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Diuretics are the longest-used\ndrugs in heart failure after digoxin.\nThis is due to their effect on the retention\nof sodium and an increase in the\nvolume of fluid in the extracellular\nspace secondary to neurohormonal\nand hemodynamic disorders occurs\nin heart failure, and their effectiveness\nin the treatment of symptomatic\nheart failure. Discontinuation of treatment\nwith diuretics or use them in too\nsmall doses is one of the causes of\nexacerbation or acute heart failure.The\neffectiveness of most of diuretics does\nnot confirm in the clinical trials, and\nthe indications for their use are often\nbased only on expert opinion. The effect\nof these drugs on morbidity and\nmortality in patients with HF was not\nexamined. Diuretics reduce shortness\nof breath and swelling. For this reasons\nit is recom-mended to use them\nin patients with signs and symptoms\nof fluid retention regardless of the left\nventricular ejection fraction.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Position of diuretics in the treatment of heart failure in light of current guidelines].\",\"authors\":\"Krzysztof Bury, Jadwiga Nessler\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Diuretics are the longest-used\\ndrugs in heart failure after digoxin.\\nThis is due to their effect on the retention\\nof sodium and an increase in the\\nvolume of fluid in the extracellular\\nspace secondary to neurohormonal\\nand hemodynamic disorders occurs\\nin heart failure, and their effectiveness\\nin the treatment of symptomatic\\nheart failure. Discontinuation of treatment\\nwith diuretics or use them in too\\nsmall doses is one of the causes of\\nexacerbation or acute heart failure.The\\neffectiveness of most of diuretics does\\nnot confirm in the clinical trials, and\\nthe indications for their use are often\\nbased only on expert opinion. The effect\\nof these drugs on morbidity and\\nmortality in patients with HF was not\\nexamined. Diuretics reduce shortness\\nof breath and swelling. For this reasons\\nit is recom-mended to use them\\nin patients with signs and symptoms\\nof fluid retention regardless of the left\\nventricular ejection fraction.</p>\",\"PeriodicalId\":21148,\"journal\":{\"name\":\"Przeglad lekarski\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad lekarski","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Position of diuretics in the treatment of heart failure in light of current guidelines].
Diuretics are the longest-used
drugs in heart failure after digoxin.
This is due to their effect on the retention
of sodium and an increase in the
volume of fluid in the extracellular
space secondary to neurohormonal
and hemodynamic disorders occurs
in heart failure, and their effectiveness
in the treatment of symptomatic
heart failure. Discontinuation of treatment
with diuretics or use them in too
small doses is one of the causes of
exacerbation or acute heart failure.The
effectiveness of most of diuretics does
not confirm in the clinical trials, and
the indications for their use are often
based only on expert opinion. The effect
of these drugs on morbidity and
mortality in patients with HF was not
examined. Diuretics reduce shortness
of breath and swelling. For this reasons
it is recom-mended to use them
in patients with signs and symptoms
of fluid retention regardless of the left
ventricular ejection fraction.