苏丹人乙型肝炎和丙型肝炎发病率和分布的实验室诊断研究

The Open Virology Journal Pub Date : 2017-10-31 eCollection Date: 2017-01-01 DOI:10.2174/1874357901711010098
Marwan M Badawi, Alshaimaa A Mohammed, Mohammed S Mohammed, Mohammed M Saeed, Elmoez Y Ali, Ashraf Khalil
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引用次数: 3

摘要

背景:乙型肝炎感染是一个令人担忧的公共卫生问题。在今天活着的人口中,几乎有20亿人在他们生命中的某个时候感染过乙肝病毒。丙型肝炎病毒是另一种威胁生命的疾病,每年约有42.5万人因其并发症而死亡。目前的研究旨在为护理人员和卫生计划人员提供5年多时间内基于年龄和性别的HBV和HCV的频率和分布的基本流行病学数据。结果:研究期间共发现2109例不同类型的患者感染HBV;男性1641例(77.81%),女性468例(22.19%),年龄以20 ~ 39岁为主(64%)。此外,16%的HBeAg检测患者被发现有反应。结论:HBV DNA水平与ALT、AST、AFP有显著相关性。在HCV感染方面,男性70例(54.9%),女性63例(45.1%),以41 ~ 60岁年龄组和基因型4为主。人们赞赏设计提高知识的活动,并在今后几年中在更大的人群中重复进行类似的研究,这将有助于找到改进的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese.

A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese.

A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese.

A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese.

Background: Hepatitis B infection is an alarming public health problem. Almost two billion people of the population alive today, would have been infected at some time in their lives by hepatitis B. Hepatitis C virus is another life threatening condition, and about 425,000 deaths occur each year due to its complications.The current study was carried out to provide care givers and health planners basic epidemiological data regarding the frequency and distribution of HBV and HCV based on age and sex during a time period of more than 5 years.

Result: A total of 2109 different patients were found to be infected by HBV during the study period; 1641 (77.81%) were males and 468 (22.19%) were females with the age group of 20-39 years predominating (64%). In addition,16% of patients tested for HBeAg were found reactive.

Conclusion: There were significant correlations observed between the levels of HBV DNA and ALT, AST and AFP. Regarding HCV, 70 males (54.9%) and 63 females (45.1%) were found to be infected, with preponderance of the age group 41 - 60 years and the genotype 4. Designing knowledge raising campaigns is appreciated as well as repetition of similar studies among larger populations in the following few years will help track a way to improvement.

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