{"title":"基底神经节回路与大脑皮层和小脑的功能解剖。","authors":"Andreea C Bostan, Richard P Dum, Peter L Strick","doi":"10.1159/000480748","DOIUrl":null,"url":null,"abstract":"<p><p>The neural connections of the basal ganglia provide important insights into their function. Here, we discuss the current perspective on basal ganglia connections with the cerebral cortex and with the cerebellum. We review the evidence that the basal ganglia participate in functionally segregated circuits with motor and non-motor areas of the cerebral cortex. We then discuss the data that the basal ganglia are interconnected with the cerebellum. These results provide the anatomical substrate for basal ganglia contributions not only to the control of movement, but also to a variety of cognitive and affective functions. Furthermore, these findings indicate that abnormal activity in basal ganglia circuits with the cerebral cortex and with the cerebellum may contribute to both motor and non-motor deficits associated with several neurologic and psychiatric conditions.</p>","PeriodicalId":39342,"journal":{"name":"Progress in neurological surgery","volume":"33 ","pages":"50-61"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000480748","citationCount":"52","resultStr":"{\"title\":\"Functional Anatomy of Basal Ganglia Circuits with the Cerebral Cortex and the Cerebellum.\",\"authors\":\"Andreea C Bostan, Richard P Dum, Peter L Strick\",\"doi\":\"10.1159/000480748\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The neural connections of the basal ganglia provide important insights into their function. Here, we discuss the current perspective on basal ganglia connections with the cerebral cortex and with the cerebellum. We review the evidence that the basal ganglia participate in functionally segregated circuits with motor and non-motor areas of the cerebral cortex. We then discuss the data that the basal ganglia are interconnected with the cerebellum. These results provide the anatomical substrate for basal ganglia contributions not only to the control of movement, but also to a variety of cognitive and affective functions. Furthermore, these findings indicate that abnormal activity in basal ganglia circuits with the cerebral cortex and with the cerebellum may contribute to both motor and non-motor deficits associated with several neurologic and psychiatric conditions.</p>\",\"PeriodicalId\":39342,\"journal\":{\"name\":\"Progress in neurological surgery\",\"volume\":\"33 \",\"pages\":\"50-61\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000480748\",\"citationCount\":\"52\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in neurological surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000480748\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2018/1/12 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in neurological surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000480748","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2018/1/12 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Functional Anatomy of Basal Ganglia Circuits with the Cerebral Cortex and the Cerebellum.
The neural connections of the basal ganglia provide important insights into their function. Here, we discuss the current perspective on basal ganglia connections with the cerebral cortex and with the cerebellum. We review the evidence that the basal ganglia participate in functionally segregated circuits with motor and non-motor areas of the cerebral cortex. We then discuss the data that the basal ganglia are interconnected with the cerebellum. These results provide the anatomical substrate for basal ganglia contributions not only to the control of movement, but also to a variety of cognitive and affective functions. Furthermore, these findings indicate that abnormal activity in basal ganglia circuits with the cerebral cortex and with the cerebellum may contribute to both motor and non-motor deficits associated with several neurologic and psychiatric conditions.
期刊介绍:
Published since 1966, this series has become universally recognized as the most significant group of books serving neurological surgeons. Volumes feature contributions from distinguished international surgeons, who brilliantly review the literature from the perspective of their own personal experience. The result is a series of works providing critical distillations of developments of central importance to the theory and practice of neurological surgery.