肺气肿和急性肺损伤中的肺内皮细胞凋亡。

4区生物学 Q3 Medicine

Advances in Anatomy Embryology and Cell Biology Pub Date : 2018-01-01 DOI:10.1007/978-3-319-68483-3_4

Eboni Chambers, Sharon Rounds, Qing Lu

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引用次数: 52

摘要

细胞凋亡在多种人类疾病的稳态和发病机制中起着重要作用。内皮细胞暴露于各种环境和内部应激，内皮细胞凋亡是这些刺激的病理生理后果。肺内皮细胞凋亡引发或促进了许多肺部疾病的进展。本章将重点介绍目前对肺内皮细胞凋亡在肺气肿和急性肺损伤(ALI)发生中的作用以及控制肺内皮细胞生死的因素的认识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury.

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Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury.

Apoptosis plays an essential role in homeostasis and pathogenesis of a variety of human diseases. Endothelial cells are exposed to various environmental and internal stress and endothelial apoptosis is a pathophysiological consequence of these stimuli. Pulmonary endothelial cell apoptosis initiates or contributes to progression of a number of lung diseases. This chapter will focus on the current understanding of the role of pulmonary endothelial cell apoptosis in the development of emphysema and acute lung injury (ALI) and the factors controlling pulmonary endothelial life and death.

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来源期刊

Advances in Anatomy Embryology and Cell Biology 生物-发育生物学

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： "Advances in Anatomy, Embryology and Cell Biology" presents critical reviews on all topical fields of normal and experimental anatomy including cell biology. The multi-perspective presentation of morphological aspects of basic biological phenomen in the human constitutes the main focus of the series. The contributions re-evaluate the latest findings and show ways for further research.