基因组医学在疾病治疗中的应用。

Kimmo Porkka, Mikko Niemi, Elli Leppä, Imre Västrik, Jukka Partanen, Jarkko Ihalainen, Sakari Jokiranta, Pasi Pöllänen
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引用次数: 0

摘要

基于病人疾病机制的详细图谱的个体化医疗正在成为治疗越来越多疾病的重要组成部分。在过去的几年中,以合理的成本确定病变细胞的异常基因组和转录组的可能性已经取得了重大进展。从一个患者身上积累的大量数据会对数据提取工具提出要求,以便能够快速、可靠地掌握影响患者治疗的基本信息。与医院信息系统相连接的计算机化决策支持系统是个体化治疗的重要组成部分。尽管基因组和其他分析信息的应用具有挑战性,但个体化药物治疗提供了更有效和更安全的治疗前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Applications of genomic medicine in the treatment of diseases.

Individualized medicine, based on a detailed mapping of the patient's disease mechanisms, is becoming an essential part of treatment for an increasing number of diseases. In the past few years, the possibility to determine the abnormal genome and transcriptome of diseased cells at a reasonable cost has been the major advance. The vast amount of data accumulated from one patient will set requirements for data extraction tools, in order to have the essential information affecting the treatment of the patient information quickly and reliably at the disposal of attending physicians. A computerized decision support system connected to the information systems of the hospital is an integral part of individualized treatment. Although the application of genomic and other profiling information is challenging, individualization of medication provides great promises more effective and safer treatment.

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