酒精，干细胞和癌症

Q2 Biochemistry, Genetics and Molecular Biology

Genes and Cancer Pub Date : 2017-09-01 DOI:10.18632/genesandcancer.156

Shoujun Gu, Bao-Ngoc Nguyen, Shuyun Rao, Shulin Li, Kirti Shetty, Asif Rashid, Vivek Shukla, Chu-Xia Deng, Lopa Mishra, Bibhuti Mishra

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引用次数: 9

摘要

酒精影响的剂量、性别和遗传易感性仍然只是部分阐明。在这篇综述中，我们总结了目前对酒精在肝脏和胃肠道癌症中作用的机制的了解。此外，本文还讨论了两种最新的途径——DNA修复和TGF-β信号通路，它们为酒精在癌症和干细胞调控中的作用提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Alcohol, stem cells and cancer.

查看原文本刊更多论文

Alcohol, stem cells and cancer.

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

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来源期刊

Genes and Cancer Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

3.90

自引率

0.00%

发文量