加纳何市医院5年回顾性研究:无症状成年人群中病毒性肝炎的流行趋势

Hepatitis research and treatment Pub Date : 2017-01-01 Epub Date: 2017-11-06 DOI:10.1155/2017/6174743
Sylvester Yao Lokpo, James Osei-Yeboah, Gameli Kwame Norgbe, Patrick Kwasi Owiafe, Felix Ayroe, Francis Abeku Ussher, Mavis Popuelle Dakorah, John Gameli Deku, Nana Yaw Barimah Manaphraim, Emmanuel Akomanin Asiamah, Tibemponi Ntoni, Prince Senyo Kwasi Nyamadi, Edward Yiadom Boakye, Roseline Avorkliyah
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引用次数: 13

摘要

背景:本研究以前瞻性献血者为研究对象,旨在评估河南省无症状成年人群病毒性肝炎(HBV和HCV)感染的负担和5年(2012-2016年)趋势。材料与方法:回顾性分析2012年1月至2016年12月4180名拟献血者的医院档案资料。人口统计变量包括年龄、性别以及居住地。获得血清感染标志物(HBV、HCV)的筛查结果。结果:普通成人无症状病毒性肝炎(HBV和HCV)感染率分别为6.94%和1.84%。女性的HBV和HCV负担(8.3%和5.0%)高于男性(6.8%和1.4%)。HBV抗原血症的年龄差异显著,年轻人群(小于20岁组)的HBV血清阳性最高为11.24%,而老年人群(大于50岁组)的HBV血清阳性最低为0.92%。结论:我市成人无症状病毒性肝炎的流行程度处于中高水平。减少负担的预防措施是迫切需要的,应该针对年轻一代。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana.

Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana.

Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana.

Background: Using prospective blood donors as a proxy, this study was aimed at estimating the burden and five-year (2012-2016) trend of viral hepatitis (HBV and HCV) infection among asymptomatic adult population in Ho.

Materials and methods: A retrospective analysis was done on secondary data extracted from the hospital archives comprising 4,180 prospective blood donors from January 2012 to December 2016. Demographic variables included age and sex, as well as place of residence. Screening results of serum infectious markers (HBV and HCV) were obtained.

Results: The prevalence of asymptomatic viral hepatitis (HBV and HCV) infection in the general adult population was 6.94% and 1.84%, respectively. Females recorded a higher burden of HBV and HCV (8.3% and 5.0%) compared to their male peers (6.8% and 1.4%). A significant age variation in HBV antigenaemia was seen with HBV seropositivity peaking among the younger population (less than 20 years' group) at 11.24% and troughed among the older population (above 50 years' group) at 0.92%.

Conclusion: Asymptomatic viral hepatitis among adult population in the Ho Municipality is estimated at the intermediate to high endemicity level. Preventive measures to reduce the burden are urgently needed and should be targeted at the younger generation.

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