{"title":"抑郁症是免疫系统异常的结果吗?","authors":"Xiaoyun Guo, Kaida Jiang","doi":"10.11919/j.issn.1002-0829.217015","DOIUrl":null,"url":null,"abstract":"<p><p>The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances.</p>","PeriodicalId":21886,"journal":{"name":"Shanghai archives of psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/c8/sap-29-171.PMC5579461.pdf","citationCount":"6","resultStr":"{\"title\":\"Is Depression the Result of Immune System Abnormalities?\",\"authors\":\"Xiaoyun Guo, Kaida Jiang\",\"doi\":\"10.11919/j.issn.1002-0829.217015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances.</p>\",\"PeriodicalId\":21886,\"journal\":{\"name\":\"Shanghai archives of psychiatry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/c8/sap-29-171.PMC5579461.pdf\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Shanghai archives of psychiatry\",\"FirstCategoryId\":\"95\",\"ListUrlMain\":\"https://doi.org/10.11919/j.issn.1002-0829.217015\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Shanghai archives of psychiatry","FirstCategoryId":"95","ListUrlMain":"https://doi.org/10.11919/j.issn.1002-0829.217015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Is Depression the Result of Immune System Abnormalities?
The etiology of Major Depressive Disorder (MDD) is still unclear. We reviewed the literature for the relationship between inflammatory signaling and cytokines in the pathogenesis of MDD. In addition, we provid evidence for adjunctive treatment using anti-inflammatory drugs to improve the therapeutic effect and prognosis. Finally, we explore the possible relationship between the pathogenesis of MDD and immune disturbances.