不孕妇女在辅助生殖周期中的血清镁和钙水平。

IF 1.5 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Elena Grossi, Sara Castiglioni, Claudia Moscheni, Patrizio Antonazzo, Irene Cetin, Valeria Maria Savasi
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引用次数: 12

摘要

镁(Mg)和钙(Ca)是女性孕前健康的必需阳离子。众所周知,在血液中,这两种阳离子的电离形式的浓度在月经周期期间会暂时改变,这表明性类固醇激素与血清钙和镁水平之间存在相关性。文献证据表明,在辅助生殖技术中,卵巢过度刺激期间增加雌激素也可能调节血清镁和钙水平。因此,我们首先检测了大量接受宫内人工授精(IUI)的不孕症患者在卵泡期的血清总镁和钙水平。结果与一组有生育能力的妇女进行了比较。随后,我们研究了卵巢过度刺激体外受精(IVF)前后不孕症患者的血清总镁和钙浓度。结果强调,在不孕妇女中,镁和钙的总血清浓度似乎没有改变。在促性腺激素的刺激下,这两个阳离子的值在卵巢刺激的女性中没有显著变化。然而,我们发现总的镁和钙水平呈下降趋势,而雌激素水平则上升。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Serum magnesium and calcium levels in infertile women during a cycle of reproductive assistance.

Magnesium (Mg) and calcium (Ca) are essential cations for women's preconception health. It is well known that, in blood, the concentration of ionized form of these two cations is temporally altered during menstrual cycle, suggesting a correlation between sex steroid hormones and serum calcium and magnesium levels. Evidence from literature suggests that in assisted reproductive technology increasing estrogens during ovarian hyperstimulation may also modulate serum magnesium and calcium levels. Therefore, we first examined total serum magnesium and calcium levels during follicular phase in a large population of infertile patients who underwent intrauterine insemination (IUI). The results were compared to a group of fertile women. Successively, we studied the total serum magnesium and calcium concentrations in infertile patients before and after ovarian hyperstimulation for in vitro fertilization (IVF). Results highlight that total serum concentration of magnesium and calcium does not seem altered in infertile women. During stimulation with gonadotropins, the values of the two cations do not change significantly in ovarian-stimulated women. However, we found a downward trend in the total magnesium and calcium levels in relation to the rising estrogens.

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来源期刊
Magnesium research
Magnesium research 医学-内分泌学与代谢
CiteScore
3.50
自引率
9.40%
发文量
6
审稿时长
>12 weeks
期刊介绍: Magnesium Research, the official journal of the international Society for the Development of Research on Magnesium (SDRM), has been the benchmark journal on the use of magnesium in biomedicine for more than 30 years. This quarterly publication provides regular updates on multinational and multidisciplinary research into magnesium, bringing together original experimental and clinical articles, correspondence, Letters to the Editor, comments on latest news, general features, summaries of relevant articles from other journals, and reports and statements from national and international conferences and symposiums. Indexed in the leading medical databases, Magnesium Research is an essential journal for specialists and general practitioners, for basic and clinical researchers, for practising doctors and academics.
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