绘制从人类患者中分离的两株柯氏葡萄球菌机会致病性菌株的基因组序列。

Q3 Biochemistry, Genetics and Molecular Biology
Standards in Genomic Sciences Pub Date : 2017-08-31 eCollection Date: 2017-01-01 DOI:10.1186/s40793-017-0263-1
Soraya Mendoza-Olazarán, José F Garcia-Mazcorro, Rayo Morfín-Otero, Licet Villarreal-Treviño, Adrián Camacho-Ortiz, Eduardo Rodríguez-Noriega, Paola Bocanegra-Ibarias, Héctor J Maldonado-Garza, Scot E Dowd, Elvira Garza-González
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引用次数: 9

摘要

在此,我们报告了从人类分离的两株柯氏葡萄球菌机会致病性菌株的基因组序列草图和注释。一株(SC-57)于2006年5月从一名男性患者的血液中分离出来,另一株(SC-532)于2006年6月从一名男性患者的导管中分离出来。与其他葡萄球菌物种的基因组相似,这两种菌株的大多数基因(42%)都参与氨基酸及其衍生物、碳水化合物和蛋白质的代谢。80个(4%)基因参与毒力、疾病和防御,这两个物种都表现出表型上低生物膜产量和与生物膜生产相关的抗生素耐药性增加的证据。从这两株葡萄球菌中均检测到新的葡萄球菌盒染色体mec: mec a类,ccr 1型。这是首次报道从人类患者中分离出的机会性柯氏球菌全基因组序列。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Draft genome sequences of two opportunistic pathogenic strains of <i>Staphylococcus cohnii</i> isolated from human patients.

Draft genome sequences of two opportunistic pathogenic strains of <i>Staphylococcus cohnii</i> isolated from human patients.

Draft genome sequences of two opportunistic pathogenic strains of Staphylococcus cohnii isolated from human patients.

Herein, we report the draft-genome sequences and annotation of two opportunistic pathogenic strains of Staphylococcus cohnii isolated from humans. One strain (SC-57) was isolated from blood from a male patient in May 2006 and the other (SC-532) from a catheter from a male patient in June 2006. Similar to other genomes of Staphylococcus species, most genes (42%) of both strains are involved in metabolism of amino acids and derivatives, carbohydrates and proteins. Eighty (4%) genes are involved in virulence, disease, and defense and both species show phenotypic low biofilm production and evidence of increased antibiotic resistance associated to biofilm production. From both isolates, a new Staphylococcal Cassette Chromosome mec was detected: mec class A, ccr type 1. This is the first report of whole genome sequences of opportunistic S. cohnii isolated from human patients.

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来源期刊
Standards in Genomic Sciences
Standards in Genomic Sciences GENETICS & HEREDITY-MICROBIOLOGY
CiteScore
1.44
自引率
0.00%
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审稿时长
6-12 weeks
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