抗逆转录病毒治疗的人类免疫缺陷病毒患者结膜菌群。

Ophthalmology and eye diseases Pub Date : 2017-08-03 eCollection Date: 2017-01-01 DOI:10.1177/1179172117724760
Kagmeni Giles, Yannick Bilong, Andin Viola Dohvoma, Steve Robert Ebana, Hortance Gonsu
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引用次数: 2

摘要

目的:了解接受抗逆转录病毒治疗(ART)的人类免疫缺陷病毒(HIV)患者结膜菌群。方法:对104名接受抗逆转录病毒治疗的HIV患者的104份结膜拭子进行微生物学评估以描述菌群。结果:女性71例(68.26%),男性33例(31.74%)。平均年龄42.9±9.77岁(22 ~ 70岁)。39例(37.50%)培养阴性。65例(62.50%)出现细菌生长。凝固酶阴性葡萄球菌59眼(90.76%),凝固酶阳性葡萄球菌3眼(4.61%)。抗逆转录病毒治疗持续时间、免疫抑制程度和细菌生长之间存在显著相关性。结论:了解HIV患者结膜菌群可为治疗眼表感染选择抗生素提供更好的指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.

Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.

Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.
Objectives: To determine the conjunctival flora of human immunodeficiency virus (HIV) patients on antiretroviral treatment (ART). Methodology: A total of 104 conjunctival swabs from 104 HIV patients on ART underwent microbiological evaluation to describe the flora. Result: There were 71 (68.26%) women and 33 (31.74%) men. The mean age was 42.9 ± 9.77 (range: 22-70) years. Negative cultures were found in 39 (37.50%) cases. Bacterial growth occurred in 65 (62.50%) cases. Coagulase-negative Staphylococcus was found in 59 eyes (90.76%), and coagulase-positive in 3 eyes (4.61%). There was a significant correlation between the duration of ART, the degrees of immunosuppression, and bacterial growth. Conclusions: Knowledge of the conjunctival flora in HIV patients may provide a better guideline in the choice of antibiotic for the management of ocular surface infections.
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