{"title":"地高辛在慢性阻塞性肺病中的药动学研究","authors":"M De Paepe, F Belpaire, Y Bogaerts","doi":"10.3109/08860228209050814","DOIUrl":null,"url":null,"abstract":"<p><p>The peritoneal elimination of digoxin during C.A.P.D. was studied in five patients. The plasma half life of digoxin varied from 54 hours to 141 hours. Only 7 to 24 micrograms was eliminated via the peritoneal route during 3 to 4 days C.A.P.D. treatment. The total urinary elimination during the same period ranged from 11 to 57 micrograms. It is concluded that adjustment of dose is not necessary when starting C.A.P.D.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050814","citationCount":"11","resultStr":"{\"title\":\"Pharmacokinetics of digoxin in C.A.P.D.\",\"authors\":\"M De Paepe, F Belpaire, Y Bogaerts\",\"doi\":\"10.3109/08860228209050814\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The peritoneal elimination of digoxin during C.A.P.D. was studied in five patients. The plasma half life of digoxin varied from 54 hours to 141 hours. Only 7 to 24 micrograms was eliminated via the peritoneal route during 3 to 4 days C.A.P.D. treatment. The total urinary elimination during the same period ranged from 11 to 57 micrograms. It is concluded that adjustment of dose is not necessary when starting C.A.P.D.</p>\",\"PeriodicalId\":79208,\"journal\":{\"name\":\"Clinical and experimental dialysis and apheresis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/08860228209050814\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and experimental dialysis and apheresis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/08860228209050814\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental dialysis and apheresis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08860228209050814","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The peritoneal elimination of digoxin during C.A.P.D. was studied in five patients. The plasma half life of digoxin varied from 54 hours to 141 hours. Only 7 to 24 micrograms was eliminated via the peritoneal route during 3 to 4 days C.A.P.D. treatment. The total urinary elimination during the same period ranged from 11 to 57 micrograms. It is concluded that adjustment of dose is not necessary when starting C.A.P.D.
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