胃肠病学从临床到转化研究的进展:肠道功能不全、康复和移植综合单元的贡献。肠道移植过程的生物医学监测及其与患者所经历的各种病理生理事件的相关性。

Q4 Medicine
Gabriel E Gondolesi, Dominik Meier, Carolina Rumbo, Diego Ramisch, Constanza Echevarría, Fabio Nachman, Melisa Pucci Molineris, María Inés Martínez, Pablo Barros Schelotto, Ana Abdurrob, Héctor Solar, Martín Rumbo
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引用次数: 0

摘要

在过去的50年里,胃肠病学和外科最伟大的成就之一就是能够将消化系统的不同腹部器官分开或作为一个整体进行移植。肠移植的复杂性需要一个多学科团队参与肠衰竭患者的管理,负责确定营养支持、康复或肠移植的需要。该团队应包括一个基础研究领域,为未解决的临床问题提供答案。本工作的目的是更新肠移植的现状,展示本中心的进展和成果;强调我们在临床领域的成就,以及转化研究和粘膜免疫学研究作为肠衰竭,康复和移植的整体单位的一部分的贡献。这里报告的数据表明,在我国和拉丁美洲,肠道移植已被确立为一种治疗选择,长期的结果使我们的服务处于世界上最好的中心的水平,使我们成为该专业的参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Avances en Gastroenterología Trasplante intestinal desde la clínica a la investigación traslacional: contribuciones de una unidad integral de insuficiencia intestinal, rehabilitación y trasplante. Seguimiento biomédico del proceso de trasplante intestinal y su correlación con los distintos eventos fisiopatológicos que atraviesa el paciente.

One of the greatest achievements in gastroenterology and surgery of the last 50 years has been the capability to transplant different abdominal organs of the digestive system separately or as a whole. The complexity of the intestinal transplantation demands a multidisciplinary team engaged in the management of patients with intestinal failure responsible for defining the need for nutritional support, rehabilitation, or intestinal transplantation. This team should include a basic research area to provide answers to unresolved clinical problems. The aim of this work is to update the current status of intestinal transplantation, and to show the progress and results of our center; emphasizing our achievements in the clinical area, and the contributions of the translational research and mucosal immunology studies as part of the integral unit of intestinal failure, rehabilitation and transplantation. The data reported here demonstrate that the intestinal transplantation has been established as a therapeutic option in our country and Latin America, with long term results that have ranked our service at the level of the best centers in the world positioning us as referent in the specialty.

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来源期刊
Acta Gastroenterologica Latinoamericana
Acta Gastroenterologica Latinoamericana Medicine-Gastroenterology
CiteScore
0.20
自引率
0.00%
发文量
47
期刊介绍: Está dedicada a la investigación clínica y básica sobre todos los aspectos del aparato digestivo, incluídos el hígado, el páncreas y la nutrición, en seres humanos adultos y niños, animales de experimentación o sistemas celulares.
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