{"title":"细胞外囊泡:自身免疫的进化贡献者。","authors":"Stergios Katsiougiannis","doi":"10.1615/ForumImmunDisTher.2016016491","DOIUrl":null,"url":null,"abstract":"<p><p>Extracellular vesicles, including microvesicles, exosomes and apoptotic bodies are recognized as carriers of pathogen-associated molecules with direct involvement in immune signaling and inflammation. Those observations have enforced the way these membranous vesicles are being considered as promising immunotherapeutic targets. In this review, we discuss the emerging roles of extracellular vesicles in autoimmunity and highlights their potential use as disease biomarkers as well as targets for the treatment and prevention of autoimmune diseases.</p>","PeriodicalId":89370,"journal":{"name":"Forum on immunopathological diseases and therapeutics","volume":"6 3-4","pages":"163-170"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396963/pdf/nihms809202.pdf","citationCount":"13","resultStr":"{\"title\":\"Extracellular Vesicles: Evolving Contributors in Autoimmunity.\",\"authors\":\"Stergios Katsiougiannis\",\"doi\":\"10.1615/ForumImmunDisTher.2016016491\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Extracellular vesicles, including microvesicles, exosomes and apoptotic bodies are recognized as carriers of pathogen-associated molecules with direct involvement in immune signaling and inflammation. Those observations have enforced the way these membranous vesicles are being considered as promising immunotherapeutic targets. In this review, we discuss the emerging roles of extracellular vesicles in autoimmunity and highlights their potential use as disease biomarkers as well as targets for the treatment and prevention of autoimmune diseases.</p>\",\"PeriodicalId\":89370,\"journal\":{\"name\":\"Forum on immunopathological diseases and therapeutics\",\"volume\":\"6 3-4\",\"pages\":\"163-170\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396963/pdf/nihms809202.pdf\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forum on immunopathological diseases and therapeutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1615/ForumImmunDisTher.2016016491\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forum on immunopathological diseases and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1615/ForumImmunDisTher.2016016491","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Extracellular Vesicles: Evolving Contributors in Autoimmunity.
Extracellular vesicles, including microvesicles, exosomes and apoptotic bodies are recognized as carriers of pathogen-associated molecules with direct involvement in immune signaling and inflammation. Those observations have enforced the way these membranous vesicles are being considered as promising immunotherapeutic targets. In this review, we discuss the emerging roles of extracellular vesicles in autoimmunity and highlights their potential use as disease biomarkers as well as targets for the treatment and prevention of autoimmune diseases.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
