手术缝合引起的黑素细胞痣。一种新型的爆发性黑素细胞痣?

Alexander C Katoulis, Dimitrios Sgouros, Giuseppe Argenziano, Efstathios Rallis, Ioannis Panayiotides, Dimitrios Rigopoulos
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引用次数: 1

摘要

背景:新生生物是一个复杂的过程,涉及多种发病机制,包括遗传因素、激素影响和紫外线辐射。创伤已被描述为另一种新生途径的触发因素。爆发性黑素细胞痣(EMN)与免疫抑制或水疱疾病有关,是一种特殊类型的痣,可能是由真皮-表皮连接的破坏和随后的静止色素细胞在再上皮化过程中的增殖引起的。主要观察:我们报告了2例患者的三个黑素细胞痣,沿着手术缝合方向重新发展,由于其他原因手术后。病变表现出特殊的皮肤镜特征,组织学显示获得性黑素细胞痣的特征。结论:这些病例可能是一种新型的发疹性痣,即手术缝合引起的痣,应纳入疤痕内新色素沉着的鉴别诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Surgical suturing-induced melanocytic nevi. A new type of eruptive melanocytic nevi?

Surgical suturing-induced melanocytic nevi. A new type of eruptive melanocytic nevi?

Surgical suturing-induced melanocytic nevi. A new type of eruptive melanocytic nevi?

Background: Nevogenesis is a complex process involving several pathogenetic mechanisms, including genetic factors, hormonal influences and UV-radiation. Trauma has been described as a triggering factor for an alternative pathway of nevogenesis. Eruptive melanocytic nevi (EMN), related either to immunosuppression or to blistering disorders, represent a special type of nevi probably induced by the disruption of the dermo-epidermal junction and consequent proliferation of quiescent pigment cells during re-epithelization.

Main observations: We report two patients with three melanocytic nevi that developed de novo along the direction of surgical suturing, following surgical operation for other reason. The lesions exhibited special dermoscopic characteristics and histology revealed features of acquired melanocytic nevi.

Conclusions: Such cases may represent a new type of eruptive nevus, the surgical suturing-induced nevus, which should be included in the differential diagnosis of new pigmentation developing within a scar.

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