调节性 B 细胞与过敏：揭示其中的联系。

IF 6.1 3区医学 Q1 ALLERGY

Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2017-03-27 DOI:10.18176/jiaci.0157

I Mota, C Martins, L M Borrego

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引用次数: 0

摘要

调节性 B（Breg）细胞是公认的免疫抑制细胞。过去几年中，文献中描述了几种具有不同表型和抑制机制的 Breg 细胞亚群。我们通过在 PubMed 上进行广泛的文献检索，回顾了 Breg 细胞在过敏症中的作用。我们描述了 B 细胞的类型和作用机制，以及它们在几种过敏性疾病（过敏性哮喘、过敏性鼻炎、食物过敏、接触性过敏和过敏性休克）的发病机制中的作用。

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Regulatory B Cells and Allergy: Uncovering the Link.

Regulatory B (Breg) cells are recognized as immunosuppressive cells. During the last few years, several subsets of Breg cells with different phenotypes and suppressive mechanisms have been described in the literature. We review the role of Breg cells in allergy based on an extensive literature search in PubMed. We describe the types and mechanisms of action of B cells and their role in the pathogenesis of several allergic diseases (allergic asthma, allergic rhinitis, food allergy, contact hypersensitivity, and anaphylaxis).

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来源期刊

Journal of Investigational Allergology and Clinical Immunology 医学-过敏

CiteScore

7.10

自引率

9.70%

发文量

135

审稿时长

6-12 weeks

期刊介绍： The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology.Journal of Investigational Allergology and Clinical Immunology publishes original works, reviews, short communications and opinions.