使能化学技术和平行合成-药物发现计划的加速器。

Q1 Pharmacology, Toxicology and Pharmaceutics

Progress in medicinal chemistry Pub Date : 2017-01-01 Epub Date: 2017-02-10 DOI:10.1016/bs.pmch.2016.11.001

A Vasudevan, A R Bogdan, H F Koolman, Y Wang, S W Djuric

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引用次数: 12

摘要

迫切需要提高制药业的整体生产率。对化学技术进行明智的投资可以对周期时间、产品成本和技术成功的可能性产生重大影响。这一观点描述了艾伯维开发和实施的一些技术，以及它们在新型支架合成和平行合成中的应用。

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Enabling Chemistry Technologies and Parallel Synthesis-Accelerators of Drug Discovery Programmes.

There is a pressing need to improve overall productivity in the pharmaceutical industry. Judicious investments in chemistry technologies can have a significant impact on cycle times, cost of goods and probability of technical success. This perspective describes some of these technologies developed and implemented at AbbVie, and their applications to the synthesis of novel scaffolds and to parallel synthesis.

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来源期刊

Progress in medicinal chemistry Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

15.60

自引率

0.00%

发文量

期刊介绍： This series has a long established reputation for excellent coverage of almost every facet of Medicinal Chemistry and is one of the most respected and instructive sources of information on the subject. The latest volume certifies to the continuing success of a unique series reflecting current progress in a broadly developing field of science.