高压氧治疗头颈部放射病人特别注意口腔和颌面治疗。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2016-09-01

Anne-Frédérique Chouinard, Luc Giasson, Michel Fortin

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引用次数: 0

摘要

虽然放射治疗是头颈癌的常用治疗方法，但骨放射性坏死(ORN)是治疗期间或治疗后的主要并发症。高压氧常被认为是一种预防和治疗性的治疗方法。在本文中，我们回顾了高压氧治疗头颈部放疗患者的文献。广泛使用这种疗法来预防和治疗ORN似乎主要基于个人信仰和经验，因为在科学文献中没有关于其功效的共识。因此，需要随机对照试验来评估高压氧治疗对头颈部放疗患者的实际影响。还需要更多的基础研究来阐明ORN的病理生理学，这反过来将有助于确定适当的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

HYPERBARIC OXYGEN THERAPY FOR HEAD AND NECK IRRADIATED PATIENTS WITH SPECIAL ATTENTION TO ORAL AND MAXILLOFACIAL TREATMENTS.

Although radiation therapy is a common treatment for head and neck cancer, osteoradionecrosis (ORN) represents a major complication during or after treatment. Hyperbaric oxygen is often mentioned as a prophylactic and therapeutic treatment for ORN. In this article, we review the literature on hyperbaric oxygen therapy in head and neck irradiated patients. The widespread use of such therapy for the prevention and treatment of ORN appears to be based mainly on personal beliefs and experience, as no consensus exists in the scientific literature about its efficacy. Randomized controlled trials are, thus, needed to assess the real impact of hyperbaric oxygen therapy in head and neck irradiated patients. More fundamental research is also needed to clarify the pathophysiology of ORN, which in turn would help identify appropriate treatments.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.