[驱虫物质:主要类别、问题、发展趋势及展望]。

M Kh Dzhafarov, F Vasilevich, A S Dovgalev, K D Imamkuliev, E A Pautova
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引用次数: 0

摘要

这篇综述按时间顺序考虑了目前可用的驱虫药物质的主要类别:早期驱虫药化合物、苯并咪唑、咪唑噻唑、四氢嘧啶、阿维菌素和米贝霉素,以及水杨酸酰苯胺。新物质(emodepside, monepantel, derquantel, tribendimidine)及其发展前景备受关注。本文讨论了驱虫药的分子作用机制、耐药性和替代的除虫方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[ANTHELMINTIC SUBSTANCES: MAIN CLASSES, PROBLEMS, TRENDS IN DEVELOPMENT AND PROSPECTS].

The review chronologically considers the main classes of the currently available anthelminthic substances: early anthelmintic compounds, benzimidazoles, imidazolthiazoles, tetrahydropyrimidines, avermectins and milbemycins, and salicylanilides. Great attention is paid to novel substances (emodepside, monepantel, derquantel, tribendimidine) and promising developments. Some aspects of the molecular mechanisms of action of anthelmintics, their resistance, and alternative dehelmintization methods are discussed.

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