[肺结核患者持续性药物性肝损害]。

Q4 Medicine

Tuberculosis and Lung Diseases Pub Date : 2010-01-01

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引用次数: 0

摘要

作者讨论了在接受抗结核治疗的患者中，与传统治疗反应轻微的严重、持续的药物性肝病相关的问题。本研究的目的是揭示药物性肝损害的本质和原因，其特点是病程严重、持续，临床和实验室表现明显，对传统治疗反应弱，并制定诊断原则。对传统疗法反应轻微的药物性肝病的严重、持续病程被证明是由肝脏中发生的一些竞争性病理过程引起的，而不是治疗和诊断过程中的失败。对于对传统治疗有轻微反应的严重、持续病程的药物性肝病的预后标准已经制定。提出了一种诊断算法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[PERSISTENT DRUG-INDUCED LIVER DAMAGES IN PATIENTS WITH PULMONARY TUBERCULOSIS].

The authors discuss the problem associated with the severe, persistent course of drug-induced liver disease slightly responsive to traditional treatment in patients receiving antituberculous therapy. The objective of the study was to reveal the essence and causes of drug-induced liver damage characterized by its severe, persistent course, evident clinical and laboratory manifestations, and a weak response to traditional therapy and to develop diagnostic principles. The severe, persistent course of drug-induced liver disease slightly responsive to traditional therapy was shown to be caused by a few competitive pathological processes occurring in the liver rather than failures in the therapeutic and diagnostic process. Prognostic criteria for the severe, persistent course of drug-induced liver disease slightly responsive to traditional therapy have been developed. A diagnostic algorithm is proposed.

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来源期刊

Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.