合成大麻素摄入后急性横纹肌溶解。

Demilade A Adedinsewo, Oluwaseun Odewole, Taylor Todd
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引用次数: 18

摘要

背景:新型精神活性物质,包括合成大麻素,正变得越来越受欢迎,越来越多的患者在急性摄入后被送往急诊室。这些物质与各种各样的不良反应有关。然而,并发症的识别、临床毒性和管理仍然具有挑战性。病例报告:我们提出的情况下,一个年轻的非洲裔美国男性谁发展严重的躁动和奇怪的行为后急性K2摄入。实验室研究显示血清肌酸磷酸激酶(CPK)明显升高,肾功能正常。患者接受积极的静脉(IV)补液治疗和基础精神疾病治疗。结论:我们建议在急性摄入合成大麻素后就诊于急诊科的患者中,在早期开始静脉补水时常规评估肾功能和CPK水平,以早期识别潜在的并发症,并制定早期支持治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute Rhabdomyolysis Following Synthetic Cannabinoid Ingestion.

Context: Novel psychoactive substances, including synthetic cannabinoids, are becoming increasingly popular, with more patients being seen in the emergency room following acute ingestion. These substances have been associated with a wide range of adverse effects. However, identification of complications, clinical toxicity, and management remain challenging.

Case report: We present the case of a young African-American male who developed severe agitation and bizarre behavior following acute K2 ingestion. Laboratory studies revealed markedly elevated serum creatine phosphokinase (CPK) with normal renal function. The patient was managed with aggressive intravenous (IV) fluid hydration and treatment of underlying psychiatric illness.

Conclusion: We recommend the routine evaluation of renal function and CPK levels with early initiation of IV hydration among patients who present to the emergency department following acute ingestion of synthetic cannabinoids to identify potential complications early as well as institute early supportive therapy.

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