治疗哮喘的最新专利。

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics
David El-Qutob, Isabela Raducan
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引用次数: 0

摘要

背景:尽管足够的坚持和完成抗哮喘治疗,许多患者仍然控制不佳或不受控制。哮喘的管理是基于使用药物来逆转支气管阻塞和消除气道炎症。随着哮喘病理生理学和机制的发现,未来有望开发新的药物。目前,对这些疾病有一套良好而有效的治疗方法。然而,寻找新的治疗方式来改善现有的治疗方法对于那些对现有治疗无反应的患者尤为重要。目的:综述近年来研究的抗细胞因子、抗白三烯分子、免疫调节和抗炎药物等治疗哮喘的新方法。方法:使用数据库专利检索2015年及2016年初有关哮喘治疗的新专利。结论:药物基因组学的观点目前正被大多数主要制药公司视为永无止境的研究方向。药物基因组学具有显著提高药物安全性和有效性的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Patents for the Treatment of Asthma.

Background: Despite adequate adherence and completion of anti-asthmatic treatment, many patients remain poorly controlled or uncontrolled. Asthma management is based on the use of medication to reverse the bronchial obstruction and eliminate the airway inflammation. New drug development is expected in the future as a consequence of discoveries in the pathophysiology and mechanisms of asthma. Currently, a good and effective set of treatments is available for these diseases. However, the search for new treatment modalities to improve the currently available is especially important for those patients unresponsive to current therapy.

Objective: In this review, we summarize new anti-cytokines therapies, anti-leucotrienes molecules, immunomodulatory and anti-inflammatory agents, researched for treatment of asthma.

Method: Database patents were used for searching new patents from 2015 and from the beginning of 2016 about treatment of asthma.

Conclusion: Pharmacogenomic point of view is now being considered by most major pharmaceutical companies as line of investigation without end in the nearest horizon. Pharmacogenomics has the potential to notably improve the safety and effectiveness of medications.

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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
期刊介绍: Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.
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