[乳酸脱氢酶水平作为窒息新生儿肾功能障碍的标志]。

Likars'ka sprava Pub Date : 2015-10-01
A M Loboda
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引用次数: 0

摘要

本文探讨了测定生物体液中乳酸脱氢酶(LD)水平作为新生儿窒息时肾功能障碍和能量供应指标的可能性。调查对象包括200例肾功能障碍足月新生儿,其中100例为重度窒息,100例为中度窒息。用动力学分光光度法测定LD活性。测定新生儿早期尿中LD的活性,作为诊断新生儿窒息肾功能不全的无创指标是可取的。血清LD含量可作为新生儿窒息肾损害的早期指标之一。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[THE LEVEL OF LACTATE DEHYDROGENASE AS A MARKER OF RENAL DYSFUNCTION IN NEONATES WITH ASPHYXIA].

The article examines the possibility of determining the level of lactate dehydrogenase (LD) in biological fluids as a marker of renal dysfunction and energy supply in neonates with asphyxia. Investigation included 200 full-term newborns with disturbance kidney function: 100 infants who had severe asphyxia, and 100--with moderate asphyxia. LD activity was determined by kinetic spectrophotometric method. Determination of the activity of LD in the urine in the early neonatal period it is advisable to use as a non-invasive marker for the diagnosis of renal dysfunction in neonates with asphyxia. The content of LD in the blood serum can be used as one of the early markers of kidney damage in newborns with asphyxia.

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