男性肺结核并发鳞状细胞肺癌。

Marcin Skowroński, Katarzyna Iwanik, Anna Halicka, Aleksander Barinow-Wojewódzki
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引用次数: 6

摘要

肺癌和肺结核非常普遍,是主要的公共卫生问题。它们具有共同的危险因素和临床表现。研究还表明,结核病预示着肺癌风险的增加,可能与肺部的慢性炎症有关。然而,如果治疗得当,它似乎不会影响肺癌的临床病程。我们报告一位57岁男性合并肺结核及肺癌的病例。他被诊断为抗酸杆菌(AFB)痰涂片阳性,随后结核分枝杆菌培养。同时伴有慢性丙型肝炎病毒(HCV)感染和外周动脉疾病(PAD)。后来,在抗结核治疗(ATT)中,鳞状细胞肺癌(SCC)通过计算机断层扫描(CT)引导活检确诊。由于患者一般情况不佳,不适合手术或根治性化疗和放疗。他被转到临终关怀医院接受缓和治疗。我们想强调的是,无论是结核病还是肺癌,患者都应该积极寻求治疗。此外,毫无疑问,这些对结核病治疗反应良好的肺癌患者应及时考虑进行适当的抗癌治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Squamous cell lung cancer in a male with pulmonary tuberculosis.

Lung cancer and pulmonary tuberculosis (TB) are highly prevalent and representing major public health issues. They share common risk factors and clinical manifestations. It is also suggested that TB predicts raised lung cancer risk likely related to chronic inflammation in the lungs. However, it does not seem to influence the clinical course of lung cancer provided that it is properly treated. We present a case report of a 57-year old male with concurrent TB and lung cancer. He was diagnosed with positive sputum smear for acid fast bacilli (AFB) and subsequent culture of Mycobacterium tuberculosis. Besides, his comorbid conditions were chronic hepatitis C virus (HCV) infection and peripheral artery disease (PAD). Later while on anti-tuberculous treatment (ATT) squamous cell lung cancer (SCC) was confirmed with computed tomography (CT) guided biopsy. Due to poor general condition the patient was not fit for either surgery or radical chemo- and radiotherapy. He was transferred to hospice for palliative therapy. We want to emphasize that both TB and lung cancer should be actively sought for in patients with either disorder. In addition, there is no doubt that these patients with lung cancer and with good response to TB treatment should be promptly considered for appropriate anticancer therapy.

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