耐甲氧西林金黄色葡萄球菌:用不耐药的表皮葡萄球菌培养物进行治疗。

Q3 Medicine
Felix-Martin Werner, Rafael Coveñas
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引用次数: 0

摘要

耐甲氧西林金黄色葡萄球菌的定植和感染是医院和长期护理机构的一个主要健康问题。虽然耐甲氧西林金黄色葡萄球菌(MRSA)菌血症可以使用万古霉素和其他储备抗生素进行治疗,但仍有 20% 的患者无法成功治愈。根据罗伯特-科赫研究所(Robert-Koch-Institute)的指导方针,医院会对定植有 MRSA 的住院病人进行隔离,但在长期护理机构,这些病人不会被紧急隔离。采取积极的去殖民化措施来根除 MRSA 定植。为了减少 MRSA 的定植,可以使用没有抗生素耐药性的表皮葡萄球菌培养物,从而将表皮葡萄球菌的生理基因传给 MRSA 细菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Methicillin-resistant Staphylococcus aureus: treatment with cultures of not drug-resistant Staphylocuccus epidermidis.

The colonization and infection with methicillin-resistant Staphylococcus aureus is a major health problem in hospitals and long-term care facilities. Although bacteriaemias with MRSA (methicillin-resistant Staphylococcus aureus) can be treated with vancomycin and other reserve antibiotics, 20% of patients cannot be successfully cured. Inpatients colonized with MRSA are isolated in hospitals according to the guidelines of the Robert-Koch-Institute, althouth in long-term care facilities these patients are not urgently isolated. Active decolonization measures are taken to eradicate colonization with MRSA. In order to reduce MRSA colonization, it could be possible to administer cultures of Staphylococcus epidermidis which have no anbitiotic resistance, so that physiological genes could be conferred from Staphylococcus epidermis to MRSA bacteria.

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来源期刊
Recent patents on anti-infective drug discovery
Recent patents on anti-infective drug discovery Medicine-Pharmacology (medical)
CiteScore
2.40
自引率
0.00%
发文量
1
期刊介绍: Recent Patents on Anti-Infective Drug Discovery publishes review articles on recent patents in the field of anti-infective drug discovery e.g. novel bioactive compounds, analogs & targets. A selection of important and recent patents on anti-infective drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-infective drug design and discovery.
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