洋甘菊油局部应用治疗儿童单症状性遗尿:一项双盲随机对照试验

Hosein Sharifi, Mohammad Bagher Minaie, Mohammad Javad Qasemzadeh, Nematollah Ataei, Mohammad Gharehbeglou, Mojtaba Heydari
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引用次数: 20

摘要

目的:评价外用苦参油治疗小儿遗尿症的疗效。方法:80例诊断为单症状性夜间或白天遗尿的患者,在平行设计的双盲随机安慰剂对照试验中,被分配到局部服用洋甘菊油或安慰剂6周。在干预前后8周对患者进行遗尿频率和任何观察到的不良事件的评估。结果:干预组患者第1、2、3周平均遗尿频次低于安慰剂组,差异均有统计学意义(P < 0.001, P = 0.03, P < 0.001)。在研究组中没有任何不良事件的报告。结论:本研究结果表明,局部应用(洋甘菊)油可降低单症状夜间或日间遗尿患儿夜尿频率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Topical use of Matricaria recutita L (Chamomile) Oil in the Treatment of Monosymptomatic Enuresis in Children: A Double-Blind Randomized Controlled Trial.

Topical use of Matricaria recutita L (Chamomile) Oil in the Treatment of Monosymptomatic Enuresis in Children: A Double-Blind Randomized Controlled Trial.

Topical use of Matricaria recutita L (Chamomile) Oil in the Treatment of Monosymptomatic Enuresis in Children: A Double-Blind Randomized Controlled Trial.

Aim: To evaluate the efficacy of topical use of Matricaria recutita L oil in the treatment of enuresis in children.

Methods: Eighty patients diagnosed as monosymptomatic nocturnal or daytime enuresis were allocated to receive Matricaria recutita L (chamomile) oil or placebo topically for 6 weeks in a double-blind randomized placebo-controlled trial with a parallel design. Patients were evaluated prior to and following 8 weeks of the intervention in terms of frequency of enuresis and any observed adverse events.

Results: The mean frequency of enuresis at the first, second, and third 2 weeks was lower in the intervention group compared with the placebo group, and the differences were statistically significant (P < .001, P = .03, and P < .001, respectively). There was no report of any adverse event in the study groups.

Conclusion: The findings of this study showed that the topical use of (chamomile) oil can decrease the frequency of nocturia in children with monosymptomatic nocturnal or daytime enuresis.

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来源期刊
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审稿时长
15 weeks
期刊介绍: The Journal of Evidence-Based Integrative Medicine ((JEBIM)), published previously as the Journal of Evidence-Based Complementary and Alternative Medicine (JEBCAM) and also as Complementary Health Practice Review (CHPR). The Journal of Evidence-Based Integrative Medicine (JEBIM) is an interdisciplinary, peer-reviewed, open access, biomedical journal whose aim is to create a global platform for hypothesis-driven and evidence-based research in all fields of integrative medicine. The journal’s objective is to publish papers which impart scientific validity to Integrative Medicine methods that are indispensable and inevitable in today’s world. All papers will be peer reviewed by experts in their respective fields, and papers will be accepted based on their scientific merit. It is the goal of the Journal to help remove the “myth” and provide scientific rationale for the various methodologies and theories of Integrative Medicine. All submissions will be reviewed based on their scientific merit and only papers with sound study design, valid statistical analyses and logical conclusions will be accepted. Topics include, but are not limited to: Traditional Eastern and Western medicine Nutrition therapy and supplementation Massage Therapy Non-traditional treatments Preventative medicine Integrative health and medicine Mindfulness Yoga.
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