维生素d的骨骼外作用——神话和事实。

Amer Sebaaly, Falah Bachour, Wael Bayoud, Gemma Adib, Farid Bedran, Clea Daher, Ghassan Maalouf
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引用次数: 0

摘要

众所周知,维生素D对骨骼代谢、钙和磷的体内平衡有影响。最近,全世界都在关注这种脂溶性维生素的骨骼外作用。《纽约时报》甚至称其为“灵丹妙药”。维生素D是脂溶性维生素,通过细胞内受体起作用。本文综述了维生素D的骨骼外作用,重点是心血管作用,葡萄糖调节,抗肿瘤特性,对免疫系统和骨骼肌的作用,并试图提供可能的分子解释这些作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE EXTRASKELETAL ACTIONS OF VITAMIN D--MYTHS AND FACTS.

Vitamin D is well known for its effects on bone metabolism, calcium and phosphorus homeostasis. Recently, a worldwide focus has been made on the extraskeletal effects of this liposoluble vitamin. The New York Times even called it the "wonder drug". Vitamin D is a liposoluble vitamin and acts via an intracellular receptor. This article reviews the extra-skeletal effects of vitamin D focusing on cardiovascular effects, regulation of glucose, antitumoral properties, and effect on the immune system and the skeletal muscle and attempts to offer possible molecular explanations to these effects.

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