[FMRP缺陷患者视觉认知功能障碍的一般和特殊机制]。

IF 0.2 4区 医学 Q4 NEUROSCIENCES
D S Pereverzeva, K K Danilina, N L Gorbachevskaya
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引用次数: 0

摘要

本文旨在对FMRP缺陷受试者的视觉认知发展进行综述。本文介绍了脆性X智力发育迟滞综合征,这是遗传性智力残疾最常见的原因,也是自闭症谱系障碍最常见的遗传原因之一。该综合征与fmr1基因突变后脆性X智力迟钝蛋白缺失有关。本文讨论了静态和动态物体感知、人脸感知和动眼力控制的研究。将FX综合征受试者的结果与具有封闭行为表型的ASD数据进行比较。本文讨论了造成视觉认知缺陷的几个因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[General and Specific Mechanisms of Visual Cognitive Function Impairment in People with FMRP Deficit].

The purpose of this article is to provide the overview of visual cognitive development in subjects with FMRP deficit. Description of fragile X mental retardation syndrome is presented in the article, that is the most common cause of inherited intellectual disability and one of the most prevalent genetic causes of autism spectrum disorder. The syndrome is associated with deficit of fragile X mental retardation protein following FMR1-gene mutation. Researches of static and dynamic object perception, face perception and oculomotor control are discussed in the article. The results obtained by subjects with FX syndrome are compared with ASD data, syndrome with closed behavioral phenotype. Several factors that underlie visual cognitive deficit are discussed in the article.

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来源期刊
CiteScore
0.70
自引率
33.30%
发文量
9
审稿时长
6-12 weeks
期刊介绍: Information not localized
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