2022年影像学在轴型脊柱炎诊断和疾病缓解评估中的应用

IF 5.7 2区 医学 Q1 RHEUMATOLOGY
Current Rheumatology Reports Pub Date : 2022-12-01 Epub Date: 2022-10-15 DOI:10.1007/s11926-022-01091-5
Ann-Sophie De Craemer, Zuzanna Łukasik, Philippe Carron
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引用次数: 2

摘要

医学影像仍然是诊断和随访轴型脊柱炎(axSpA)患者的基石。由于缺乏能够监测疾病活动和进展的特异性生物标志物,临床医生参考成像模式来准确评估axSpA负担。技术进步和现代成像技术(如核磁共振成像)的日益普及,使这种疾病的诊断速度更快,因此大大改变了诊断延迟,改善了axSpA患者的预后和功能结果。活动性骶髂炎的MRI影像已被广泛接受为一种诊断工具,并且已经开发了轴向骨骼内炎症和结构性病变的定义。最近,骨髓水肿(提示骶髂炎)在非spa患者中很常见,可归因于机械负荷或健康个体随着年龄的增长而积累。因此,区分真实的病理和隐藏的影像学表现是至关重要的,这不仅是为了诊断,也是为了缓解疾病。新的成像模式,旨在体内特定分子过程的可视化,可以用来交叉验证日常临床实践中使用的技术的发现。这篇综述批判性地评估了2022年axSpA中不同影像学诊断和疾病缓解评估的使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Use of Imaging in Axial Spondyloarthritis for Diagnosis and Assessment of Disease Remission in the Year 2022.

Use of Imaging in Axial Spondyloarthritis for Diagnosis and Assessment of Disease Remission in the Year 2022.

Medical imaging remains the cornerstone of diagnostics and follow-up of axial spondyloarthritis (axSpA) patients. With the lack of specific biomarkers allowing monitoring of disease activity and progression, clinicians refer to imaging modalities for accurate evaluation of the axSpA burden. Technological advances and increasing availability of modern imaging techniques such as MRI have enabled faster diagnosis of the disease, hence dramatically changed the diagnostic delay and improved the prognosis and functional outcomes for axSpA patients.Active sacroiliitis as visualized by MRI has been widely accepted as a diagnostic tool, and definitions of inflammatory and structural lesions within the axial skeleton have been developed. Recently, it has been acknowledged that bone marrow edema, suggestive of sacroiliitis, is a common finding among non-SpA patients, and could be attributed to mechanical loading or accumulate with age in healthy individuals. Therefore, it is crucial to distinguish between true pathological and concealing imaging findings, not only for diagnostic but also for disease remission purposes. New imaging modalities, aimed for in vivo visualization of specific molecular processes, could be employed to cross-validate findings from techniques used in daily clinical practice. This review critically evaluates the use of different imaging modalities for diagnosis and assessment of disease remission in axSpA in the year 2022.

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来源期刊
CiteScore
11.20
自引率
0.00%
发文量
41
期刊介绍: This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.
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