[BCR-ABL1阴性慢性髓性白血病2例报告]。

IF 0.5 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Revista medica de Chile Pub Date : 2022-03-01 DOI:10.4067/S0034-98872022000300397

Fernanda Figueroa-Faúndez, Catalina Vidal-Rojas, Vania Briones-Muñoz, Mauricio Chandía-Cabas

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引用次数: 0

摘要

BCR-ABL1阴性非典型慢性髓性白血病(aCML)是一种罕见的骨髓增生/骨髓增生异常综合征，其特征是在BCR-ABL1融合基因缺乏阳性的情况下，白细胞增多和增生异常的嗜中性粒细胞前体。我们报告了一名66岁女性和一名57岁男性aCML患者，他们最初表现为全身不适和体重减轻，伴有贫血、血小板减少、白细胞增多、左移和中性粒细胞系列发育不良。入院后，两例患者均发展不良，几天后因多器官衰竭死亡。

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[BCR-ABL1 negative chronic myeloid leukemia: report of two cases].

BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure.

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来源期刊

Revista medica de Chile 医学-医学：内科

CiteScore

1.20

自引率

16.70%

发文量

审稿时长

3-6 weeks

期刊介绍： La Revista Médica de Chile publica trabajos originales sobre temas de interés médico y de Ciencias Biomédicas, dando preferencia a los relacionados con la Medicina Interna y sus especialidades derivadas. Publicada mensualmente, desde 1872, por la Sociedad Médica de Santiago. La abreviatura de su título es Rev Med Chile, que debe ser usado en bibliografías, notas al pié de página, leyendas y referencias bibliográficas.