COVID-19 严重急性呼吸系统综合征的心血管并发症。

IF 1.3
American journal of cardiovascular disease Pub Date : 2022-08-15 eCollection Date: 2022-01-01
Robert J Henning
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引用次数: 0

摘要

截至 2022 年 9 月 7 日,全球已报告 COVID-19 确诊病例 603,711,760 例,6,484,136 人死于 COVID-19 并发症。值得注意的是,自大流行开始以来,奥米克龙变异体产生的与COVID-19相关的住院人数最多。在 COVID-19 的住院患者中,≥20% 的患者会出现心脏损伤,17% 至 44% 的患者会出现心律失常,22% 至 40% 的患者会出现心脏损伤并伴有血肌钙蛋白升高,2% 至 7% 的患者会出现心肌炎,4% 至 21% 的患者会出现心力衰竭,15% 至 39% 的患者会出现血栓栓塞事件。心脏并发症的风险因素包括年龄大于 70 岁、男性、体重指数≥30 kg/m2、糖尿病、既往患有心血管疾病以及入院时患有中度至重度肺炎。感染 COVID-19 并导致血液肌钙蛋白浓度显著升高的既往心血管疾病患者的死亡率高达 69%。本综述主要介绍 COVID-19 的发病率、CoV-2 对心血管系统损伤的病理生理机制以及目前对 COVID-19 住院患者推荐的治疗方法,以便医务人员降低 COVID-19 患者的发病率和死亡率,并有效治疗 Covid 和 Covid 后综合征患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiovascular complications of COVID-19 severe acute respiratory syndrome.

603,711,760 confirmed cases of COVID-19 have been reported throughout the world and 6,484,136 individuals have died from complications of COVID-19 as of September 7, 2022. Significantly, the Omicron variant has produced the largest number of COVID-19 associated hospitalizations since the beginning of the pandemic. Cardiac injury occurs in ≥20% of the hospitalized patients with COVID-19 and is associated with cardiac dysrhythmias in 17 to 44%, cardiac injury with increases in blood troponin in 22 to 40%, myocarditis in 2 to 7%, heart failure in 4 to 21%, and thromboembolic events in 15 to 39%. Risk factors for cardiac complications include age >70 years, male sex, BMI ≥30 kg/m2, diabetes, pre-existing cardiovascular disease, and moderate to severe pneumonia at hospital presentation. Patients with prior cardiovascular disease who contract COVID-19 and experience a significant increase in their blood troponin concentration are at risk for mortality rates as high as 69%. This review focuses on the prevalence, the pathophysiologic mechanisms of CoV-2 injury to the cardiovascular system and the current recommended treatments in hospitalized patients with COVID-19 in order that medical personnel can decrease the morbidity and mortality of patients with COVID-19 and effectively treat patients with Covid and post Covid syndrome.

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来源期刊
American journal of cardiovascular disease
American journal of cardiovascular disease CARDIAC & CARDIOVASCULAR SYSTEMS-
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