分子生物学史学中的一些悖论**

IF 0.6 2区哲学 Q2 HISTORY & PHILOSOPHY OF SCIENCE

Berichte zur Wissenschaftsgeschichte Pub Date : 2022-09-09 DOI:10.1002/bewi.202200025

Soraya de Chadarevian

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引用次数: 1

摘要

就在分子生物学有望实现一些长期承诺的医学应用——想想mRNA疫苗、单克隆抗体药物、PCR检测和基因治疗——的时候，分子生物学的历史已经失去了它的大部分光彩。不久以前，这个研究领域似乎是一个充满无限可能性的新兴领域，现在却常常沦为“中心教条”，在人类基因组测序的努力中看到了它的神化，但后来却被解开了。这篇文章将讨论几个可能的答案来解释这个明显的悖论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Of Some Paradoxes in the Historiography of Molecular Biology**

Just when molecular biology is arguably delivering on some of its long-promised medical applications—think mRNA vaccines, monoclonal antibody drugs, PCR testing, and gene therapies—the history of molecular biology has lost much of its shine. What not too long ago seemed like a burgeoning field of research with endless possibilities, is now often reduced to the “central dogma” that saw its apotheosis in the effort to sequence the human genome but has since unraveled. The essay will discuss several possible answers to this apparent paradox.

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来源期刊

Berichte zur Wissenschaftsgeschichte 社会科学-科学史与科学哲学

CiteScore

0.80

自引率

16.70%

发文量

审稿时长

>12 weeks

期刊介绍： Die Geschichte der Wissenschaften ist in erster Linie eine Geschichte der Ideen und Entdeckungen, oft genug aber auch der Moden, Irrtümer und Missverständnisse. Sie hängt eng mit der Entwicklung kultureller und zivilisatorischer Leistungen zusammen und bleibt von der politischen Geschichte keineswegs unberührt.