澳大利亚成人血清PINP和CTX的统一参考区间。

Q1 Biochemistry, Genetics and Molecular Biology

Clinical Biochemist Reviews Pub Date : 2014-11-01

Samuel D Vasikaran, Sa Paul Chubb, Peter R Ebeling, Nicole Jenkins, Graham Rd Jones, Mark A Kotowicz, Howard A Morris, Hans-Gerhard Schneider, Markus J Seibel, Greg Ward

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引用次数: 0

摘要

骨转换标志物(BTMs)分为形成标志物和再吸收标志物。它们在成人血液或尿液中的浓度被认为反映了骨重塑的速度，并可能用于骨病患者的管理。btm存在主要的方法间差异，目前正在国际一级寻求方法的统一。基于已发表的数据，本文描述了澳大利亚成年人血清I型胶原氨基末端前肽(s-PINP)和血清I型胶原β-异构羧基末端交联末端肽(s-CTX)的年龄和性别共识参考区间。

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Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults.

Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).

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Clinical Biochemist Reviews Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry

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