Cinnarizine:综合概况。

Q1 Pharmacology, Toxicology and Pharmaceutics

Profiles of drug substances, excipients, and related methodology Pub Date : 2015-01-01 Epub Date: 2015-04-01 DOI:10.1016/bs.podrm.2015.01.001

Nadia G Haress

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引用次数: 14

摘要

肉桂嗪是一种哌嗪衍生物，具有抗组胺、抗血清素、抗多巴胺和钙通道阻断活性。对肉桂碱进行了全面的介绍，包括它的描述和不同的分析方法。采用1H NMR和13C一、二维NMR方法。红外和质谱分析均证实了肉桂碱的结构。

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Cinnarizine: Comprehensive Profile.

Cinnarizine is a piperazine derivative with antihistaminic, antiserotonergic, antidopaminergic, and calcium channel-blocking activities. A comprehensive profile was performed on cinnarizine including its description and the different methods of analysis. The 1H NMR and 13C one- and two-dimensional NMR methods were used. In addition, infrared and mass spectral analyses were performed which all confirmed the structure of cinnarizine.

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来源期刊

Profiles of drug substances, excipients, and related methodology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

13.10

自引率

0.00%

发文量