mydrin-P与复方tropicamide在早产儿视网膜病变筛查中的效果比较。

眼科学报 Pub Date : 2014-12-01

Shuke Luo, Zhonghe Wan, Xiaofang Yin, Zuke Ye, Yan Lu

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引用次数: 0

摘要

目的:观察和比较Mydrin-P与复方托品酰胺瞳孔扩张在早产儿视网膜病变筛查中的作用。方法:以早产儿右眼滴入My- drin-P滴眼液为治疗组，左眼滴入复方托品酰胺为对照组。每5分钟滴眼3次。观察瞳孔大小，并记录于10、15、20分钟后给眼。结果:治疗组和对照组的平均瞳孔直径分别在10(6.24±0.72 mm vs 6.24±0.68 mm, t = 0.00, P = 1.00)、15(6.83±0.55 mm vs 6.78±0.54 mm, t = 1.75, P = 0.083)和20 min(7.22±0.40 mm vs 7.15±0.50 mm, t = 1.62, P = 0.109)时无显著差异。然而，两组在任意两个时间点的平均瞳孔大小有显著差异(均P < 0.001)。结论:Mydrin-P与复方托品酰胺筛查早产儿视网膜病变的临床疗效相近。筛检的最佳时间为虫蛀后20 min。

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Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.

Purpose: To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.

Methods: The right eyes of premature infants received My- drin-P eye drops as the treatment group, whereas the left eyes were administered with compound tropicamide as the control group. The eye drops were delivered every 5 min for three times. The pupil size was observed and recorded at 10, 15, and 20 min after administering mydriasis.

Results: The mean pupil diameter did not significantly differ between the treatment and control groups at 10 (6.24 ± 0.72 mm vs. 6.24 ± 0.68 mm, t = 0.00, P = 1.00), 15 (6.83 ± 0.55 mm vs. 6.78 ± 0.54 mm, t = 1.75, P = 0.083) or 20 min (7.22 ± 0.40 mm vs. 7.15 ± 0.50 mm, t = 1.62, P = 0.109), respectively. How- ever, the mean pupil size at any two time points significantly differed in both groups (all P < 0.001).

Conclusion: Both Mydrin-P and compound tropicamide exert similar clinical efficacy in the screening of retinopathy of pre- maturity. The most appropriate time for screening was at 20 min after mydriasis.

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来源期刊

眼科学报

自引率

0.00%

发文量

1312

期刊介绍： Eye science was founded in 1985. It is a national medical journal supervised by the Ministry of Education of the People's Republic of China, sponsored by Sun Yat-sen University, and hosted by Sun Yat-sen University Zhongshan Eye Center (in October 2020, it was changed from a quarterly to a monthly, with the publication number: ISSN: 1000-4432; CN: 44-1119/R). It is edited by Ge Jian, former dean of Sun Yat-sen University Zhongshan Eye Center, Liu Yizhi, director and dean of Sun Yat-sen University Zhongshan Eye Center, and Lin Haotian, deputy director of Sun Yat-sen University Zhongshan Eye Center, as executive editor. It mainly reports on new developments and trends in the field of ophthalmology at home and abroad, focusing on basic research in ophthalmology, clinical experience, and theoretical knowledge and technical operations related to epidemiology. It has been included in important databases at home and abroad, such as Chemical Abstract (CA), China Journal Full-text Database (CNKI), China Core Journals (Selection) Database (Wanfang), and Chinese Science and Technology Journal Database (VIP).