成纤维细胞对窦房结细胞电活动影响的计算机模拟。

Biofizika Pub Date : 2015-03-01

A S Tolstokorov, R A Syunyaev, R R Aliev

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引用次数: 0

摘要

通过与成纤维细胞间隙连接相互作用的窦房结细胞电活动的计算机模拟显示，与成纤维细胞相互作用导致窦房结细胞振荡频率增大。我们发现成纤维细胞也能降低内在中枢细胞的振荡幅度或完全抑制其自发活动，而对周围细胞的振荡幅度影响微弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Computer simulation of fibroblast effect on electrical activity in sinoatrial node cells].

Computer simulation of the electrical activity in sinoatrial node cells interacting via gap junctions with fibroblasts revealed that interaction with fibroblasts results in greater oscillation frequency of sinoatrial node cells. We have found out that fibroblasts also decrease the oscillation amplitude of the intrinsic central cells or completely suppress their spontaneous activity, while weakly affect the oscillation amplitude of peripheral cells.

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Biofizika

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