人类炭疽是一种重新出现的疾病。

Q3 Medicine
Mehmet Doganay, Hayati Demiraslan
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引用次数: 50

摘要

炭疽主要是食草动物的疾病,病原体是炭疽杆菌,这是一种革兰氏阳性,需氧,孢子形成,棒状细菌。炭疽芽孢杆菌孢子对高温、高压、紫外线和电离辐射、化学制剂和消毒剂具有很强的抵抗力。由于这些原因,炭疽芽孢杆菌孢子作为生物武器和/或生物恐怖主义的生物制剂是一个有吸引力的选择。土壤是传染因子的主要储存库。这种疾病最常见于野生和家养哺乳动物。人类通过接触受感染的动物和受污染的动物产品或直接暴露于炭疽芽孢杆菌孢子而继发感染。炭疽热在世界各地都有发生。在世界某些地区,这种感染在动物和人类中仍然是地方性或高地方性的;特别是在中东、西非、中亚、印度部分地区和南美洲。然而,一些国家声称没有炭疽,炭疽在西方国家已成为一种重新出现的疾病。目前,炭疽根据其设定分为(1)自然发生的炭疽,(2)与生物恐怖主义有关的炭疽。世界上绝大多数的人类炭疽是自然发生的炭疽。它也是西方国家的一种威胁疾病。本文就其相关专利、近期历史、微生物学和流行病学特征、临床表现和治疗进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Human anthrax as a re-emerging disease.

Anthrax is primarily a disease of herbivores and the etiological agent is B. anthracis which is a gram-positive, aerobic, spore-forming, and rod shaped bacterium. Bacillus anthracis spores are highly resistant to heat, pressure, ultraviolet and ionizing radiation, chemical agents and disinfectants. For these reasons, B. anthracis spores are an attractive choice as biological agents for the use of bioweapon and/or bioterrorism. Soil is the main reservoir for the infectious agent. The disease most commonly affects wild and domestic mammals. Human are secondarily infected by contact with infected animals and contaminated animal products or directly expose to B. anthracis spores. Anthrax occurs worldwide. This infection is still endemic or hyperendemic in both animals and humans in some part of areas of the world; particularly in Middle East, West Africa, Central Asia, some part of India, South America. However, some countries are claiming free of anthrax, and anthrax has become a re-emerging disease in western countries with the intentional outbreak. Currently, anthrax is classified according to its setting as (1) naturally occurring anthrax, (2) bioterrorism-related anthrax. Vast majority of human anthrax are occurring as naturally occurring anthrax in the world. It is also a threaten disease for western countries. The aim of this paper is to review the relevant patents, short historical perspective, microbiological and epidemiological features, clinical presentations and treatment.

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来源期刊
Recent patents on anti-infective drug discovery
Recent patents on anti-infective drug discovery Medicine-Pharmacology (medical)
CiteScore
2.40
自引率
0.00%
发文量
1
期刊介绍: Recent Patents on Anti-Infective Drug Discovery publishes review articles on recent patents in the field of anti-infective drug discovery e.g. novel bioactive compounds, analogs & targets. A selection of important and recent patents on anti-infective drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-infective drug design and discovery.
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