阿达木单抗诱导地衣类药物皮疹。

Constantin El Habr, Zarouwi Meguerian, Rita Sammour
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引用次数: 4

摘要

肿瘤坏死因子(TNF)-α抑制剂正被广泛和越来越多地用于治疗一系列对常规疾病修饰抗风湿药物难治性的风湿病。使用TNF-α抑制剂治疗后,有各种皮肤副作用的报道。我们报告了一例26岁的男性患者,他在开始阿达木单抗治疗克罗恩病几个月后出现地衣样物质爆发。我们还强调了地衣样药物疹和特发性扁平地衣的临床和组织病理学差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adalimumab-induced lichenoid drug eruption.

Tumor necrosis factor (TNF)-α inhibitors are being widely and increasingly used for the management of a spectrum of rheumatologic diseases that are refractory to conventional disease modifying anti-rheumatic drugs. Various cutaneous side effects have been reported after treatment with TNF-α inhibitors. We present a case report of a 26-year-old male patient who developed a lichenoid drug eruption few months after the initiation of adalimumab for the management of Crohn's disease. We also highlight the clinical and histopathologic differences between lichenoid drug eruptions and idiopathic lichen planus.

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