[BIS值对急性维生素a中毒患者意识恢复的评价:附1例报告]。

Hironori Matsumoto, Kensuke Umakoshi, Satoshi Kikuchi, Jun Takeba, Mayuki Aibiki
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引用次数: 0

摘要

一名37岁男性因急性苯巴比妥中毒入院。到达时,他处于深度昏迷状态,伴有呼吸循环抑制。血清浓度升高至149.04 μg/mL,符合致死浓度水平。他接受了洗胃、给药活性炭、尿碱化和肠冲洗。呼吸循环状态恢复迅速,而血清苯巴比妥浓度下降不顺利。药物浓度虽降至昏迷状态77.07 μg/mL,但BIS值逐渐升高,最终患者恢复意识。由于他长期服用含维生素a的苯巴比妥,血清水平可能与症状无关。BIS值能较好地反映意识水平,可作为预测急性催眠药中毒深度昏迷患者意识水平的有效指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[BIS values were useful on the evaluation of consciousness recovery in acute Vegetamin-A poisoning: report of a case].

A 37-year-old man was admitted to our hospital with acute phenobarbital poisoning. On arrival, he was in deep coma with respiro-circulatory depressions. The serum concentration of the agent was elevated to 149.04 μg/mL which was consistent with a lethal concentration level. He underwent a gastric lavage, administration of activated charcoal, urinary alkalinazation and bowel irrigation. Respiro-circulatory status was recovered rapidly, while the serum concentration of phenobarbital did not decrease smoothly. Although the concentration of the agent decreased to 77.07 μg/mL that should be a comatose level, BIS values were gradually elevated, and then eventually the patient regained his consciousness. Because he was a chronic user of Vegetamin-A containing phenobarbital, the serum level might not have been correlated with symptoms. BIS values were highly reflective of the consciousness level, so it could be a useful indicator for predicting the consciousness levels of patients in deep coma with acute poisoning from hypnotic agents.

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