河南汉族人群15个Y染色体STR位点的遗传多态性及单倍型分析

IF 2.1 3区生物学 Q3 GENETICS & HEREDITY

Hereditas Pub Date : 2015-01-14 DOI:10.1111/hrd2.00067

Xiu-Hua Zhang, Wen-Bo Zhang, Xue-Hui Fan

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引用次数: 3

摘要

研究并建立了河南省汉族人群102例无亲缘关系健康男性个体的15个Y-STRs (DYS438、DYS446、DYS391、DYS390、DYS458、DYS534、DYS426、DYS626、DYS504、DYS505、DYS576、DYS532、DYS594、DYS522、DYS540) DNA数据库。计算汉族人群的等位基因频率和统计参数。共检测到90个等位基因，对应的等位基因频率范围为0.0098 ~ 0.9020。共发现102个单倍型，其中15个Y-STR基因座的单倍型多样性为1。本研究的结果对人类鉴定和亲子鉴定在该地区的常规法医应用具有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Genetic polymorphism of 15 Y chromosomal STR loci and haplotypes of Henan Han population

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Genetic polymorphism of 15 Y chromosomal STR loci and haplotypes of Henan Han population

We studied and established a DNA database of 15 Y-STRs (DYS438, DYS446, DYS391, DYS390, DYS458, DYS534, DYS426, DYS626, DYS504, DYS505, DYS576, DYS532, DYS594, DYS522, DYS540) in a population sample of 102 unrelated, healthy, male individuals of Henan Han population. Allelic frequencies and statistical parameters of Han population were calculated. Totally 90 alleles were observed, with the corresponding allelic frequencies ranging from 0.0098 to 0.9020. 102 haplotypes were found in the studied group, the haplotype diversity for 15 Y-STR loci was 1. The results of present study were valuable for human identification and paternity tests routine forensic applications in the region.

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来源期刊

Hereditas 生物-遗传学

CiteScore

4.30

自引率

3.70%

发文量

审稿时长

6 weeks

期刊介绍： For almost a century, Hereditas has published original cutting-edge research and reviews. As the Official journal of the Mendelian Society of Lund, the journal welcomes research from across all areas of genetics and genomics. Topics of interest include human and medical genetics, animal and plant genetics, microbial genetics, agriculture and bioinformatics.