1-芳基-5-(邻甲氧基苯基)-2- s -苄基异硫脲的合成、抗菌及抗癌评价

International Journal of Medicinal Chemistry Pub Date : 2014-01-01 Epub Date: 2014-11-20 DOI:10.1155/2014/352626

Mohammed M Ansari, Shirish P Deshmukh, Rizwan Khan, Mohammed Musaddiq

引用次数: 11

摘要

一系列s -苄基芳基硫脲与邻甲氧基苯基异氰酸酯缩合，得到了相应的异硫脲衍生物。新合成的化合物通过(1)H-NMR、IR和质谱进行了表征，并进行了生物活性测试。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis Antimicrobial and Anticancer Evaluation of 1-Aryl-5-(o-methoxyphenyl)-2-S-benzyl Isothiobiurets.

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Synthesis Antimicrobial and Anticancer Evaluation of 1-Aryl-5-(o-methoxyphenyl)-2-S-benzyl Isothiobiurets.

A series of S-benzyl aryl thiourea were condensed with o-Methoxy phenyl isocyanate to yield respective isothiobiuret derivatives. The newly synthesized compounds were characterized by (1)H-NMR, IR, and Mass Spectral studies and tested for biological activities.

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来源期刊

International Journal of Medicinal Chemistry CHEMISTRY, MEDICINAL-

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期刊介绍： International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis. International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis.