Joanna Nasr, Alfred Ammoury, Camil Chouairy, Halal Mégarbané, Constantin El Habr
{"title":"药物诱导的线性IgA大疱性皮肤病模拟中毒性表皮坏死松解。","authors":"Joanna Nasr, Alfred Ammoury, Camil Chouairy, Halal Mégarbané, Constantin El Habr","doi":"10.12816/0006220","DOIUrl":null,"url":null,"abstract":"<p><p>Linear IgA bullous dermatosis (LAD) is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-induced LAD that clinically mimicked toxic epidermal necrolysis (TEN).</p>","PeriodicalId":430072,"journal":{"name":"Le Journal médical libanais. The Lebanese medical journal","volume":"62 3","pages":"176-9"},"PeriodicalIF":0.0000,"publicationDate":"2014-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Drug-induced linear IgA bullous dermatosis simulating toxic epidermal necrolysis.\",\"authors\":\"Joanna Nasr, Alfred Ammoury, Camil Chouairy, Halal Mégarbané, Constantin El Habr\",\"doi\":\"10.12816/0006220\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Linear IgA bullous dermatosis (LAD) is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-induced LAD that clinically mimicked toxic epidermal necrolysis (TEN).</p>\",\"PeriodicalId\":430072,\"journal\":{\"name\":\"Le Journal médical libanais. The Lebanese medical journal\",\"volume\":\"62 3\",\"pages\":\"176-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Le Journal médical libanais. The Lebanese medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12816/0006220\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Le Journal médical libanais. The Lebanese medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12816/0006220","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Drug-induced linear IgA bullous dermatosis simulating toxic epidermal necrolysis.
Linear IgA bullous dermatosis (LAD) is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-induced LAD that clinically mimicked toxic epidermal necrolysis (TEN).
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