TCGA将胃癌分为四种分子亚型:个体化治疗的意义。

Q Medicine

癌症 Pub Date : 2014-10-01 Epub Date: 2014-09-16 DOI:10.5732/cjc.014.10117

Wei Zhang

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引用次数: 38

摘要

胃癌是世界上癌症死亡的主要原因。胃癌的治疗是具有挑战性的，因为其高度异质性的病因和临床特点。最近胃癌的基因组和分子特征，特别是癌症基因组图谱(TCGA)的发现，揭示了四种不同亚型胃癌的异质性和潜在的靶向治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

TCGA divides gastric cancer into four molecular subtypes: implications for individualized therapeutics.

Gastric cancer is a leading cause of cancer deaths in the world. The treatment of gastric cancer is challenging because of its highly heterogeneous etiology and clinical characteristics. Recent genomic and molecular characterization of gastric cancer, especially the findings reported by the Cancer Genome Atlas (TCGA), have shed light on the heterogeneity and potential targeted therapeutics for four different subtypes of gastric cancer.

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来源期刊

癌症 ONCOLOGY-

CiteScore

3.47

自引率

0.00%

发文量

9010

审稿时长

12 weeks

期刊介绍： In July 2008, Landes Bioscience and Sun Yat-sen University Cancer Center began co-publishing the international, English-language version of AI ZHENG or the Chinese Journal of Cancer (CJC). CJC publishes original research, reviews, extra views, perspectives, supplements, and spotlights in all areas of cancer research. The primary criteria for publication in CJC are originality, outstanding scientific merit, and general interest. The Editorial Board is composed of members from around the world, who will strive to maintain the highest standards for excellence in order to generate a valuable resource for an international readership.