运动免疫学与MiRNAs。

IF 3.5 4区医学 Q2 IMMUNOLOGY

Exercise Immunology Review Pub Date : 2014-01-01

Julia A Makarova, Diana V Maltseva, Vladimir V Galatenko, Asghar Abbasi, Daniil G Maximenko, Anatoly I Grigoriev, Alexander G Tonevitsky, Hinnak Northoff

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引用次数: 0

摘要

大量证据表明，不同类型的身体活动会改变蛋白质编码基因的表达。近年来揭示了非编码rna介导的细胞过程的另一个水平的调节。MicroRNAs (miRNAs)是最大的非编码rna家族之一。MiRNAs介导基因表达的转录后调控。支持mirna在免疫和其他身体系统适应运动中的关键作用的数据量稳步增长。mirna在运动后改变其表达谱，似乎参与了免疫细胞和其他细胞类型中运动反应基因的调节。在这里，我们讨论现有的数据和未来的方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Exercise immunology meets MiRNAs.

A large body of evidence indicates modified expression of protein-coding genes in response to different kinds of physical activity. Recent years have exposed another level of regulation of cellular processes mediated by non-coding RNAs. MicroRNAs (miRNAs) are one of the largest families of non-coding RNAs. MiRNAs mediate post-transcriptional regulation of gene expression. The amount of data supporting the key role of miRNAs in the adaptation of the immune and other body systems to exercise steadily grows. MiRNAs change their expression profiles after exercise and seem to be involved in regulation of exercise-responsive genes in immune and other cell types. Here we discuss existing data and future directions in the field.

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来源期刊

Exercise Immunology Review 医学-免疫学

CiteScore

16.00

自引率

0.00%

发文量

期刊介绍： Exercise Immunology Review (EIR) serves as the official publication of the International Society of Exercise and Immunology and the German Society of Sports Medicine and Prevention. It is dedicated to advancing knowledge in all areas of immunology relevant to acute exercise and regular physical activity. EIR publishes review articles and papers containing new, original data along with extensive review-like discussions. Recognizing the diverse disciplines contributing to the understanding of immune function, the journal adopts an interdisciplinary approach, facilitating the dissemination of research findings from fields such as exercise sciences, medicine, immunology, physiology, behavioral science, endocrinology, pharmacology, and psychology.