人类蛋白ALX4、ZHX1和CASP8AP2同源结构域的溶液核磁共振结构有助于人类癌症蛋白相互作用网络的结构覆盖。

Xianzhong Xu, Surya V S R K Pulavarti, Alexander Eletsky, Yuanpeng Janet Huang, Thomas B Acton, Rong Xiao, John K Everett, Gaetano T Montelione, Thomas Szyperski
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引用次数: 1

摘要

对人蛋白ALX4、ZHX1和CASP8AP2三个同源结构域的高质量溶液NMR结构进行了解析。这些领域被选为东北结构基因组学联盟追求的生物医学主题项目的目标。这个项目的重点是增加与癌症相关的人类蛋白质的结构覆盖范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.

High-quality solution NMR structures of three homeodomains from human proteins ALX4, ZHX1 and CASP8AP2 were solved. These domains were chosen as targets of a biomedical theme project pursued by the Northeast Structural Genomics Consortium. This project focuses on increasing the structural coverage of human proteins associated with cancer.

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