在资源有限的情况下,性传播感染的综合征与实验室诊断。

ISRN AIDS Pub Date : 2014-03-05 eCollection Date: 2014-01-01 DOI:10.1155/2014/103452
Musie Ghebremichael
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引用次数: 25

摘要

性传播感染在撒哈拉以南非洲非常普遍,那里有严重的艾滋病毒流行。因此,准确识别和诊断性传播感染对该地区成功的艾滋病毒预防规划至关重要。由于该区域缺乏训练有素的人员和适当的实验室基础设施,关于性传播感染概况的信息主要依赖于自我报告或医生诊断的症状。该研究的主要目的是评估性传播感染综合征诊断的有效性,在撒哈拉以南非洲和其他资源有限的环境中,这通常被用作性传播感染实验室诊断的替代方法。这项研究建立在以前从坦桑尼亚北部社区调查收集的数据基础上。我们发现在患者报告的性传播感染症状和实验室确认的性传播感染检测之间没有显著的一致。报告的性传播感染症状具有高特异性(范围= 85-99%)和低敏感性(范围= 2-17%)。从我们的研究中获得的知识将具有重要的公共卫生意义,并有助于改善性传播感染的综合征诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Resource-Limited Settings.

The Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Resource-Limited Settings.

The Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Resource-Limited Settings.

The Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Resource-Limited Settings.

Sexually transmitted infections (STIs) are highly prevalent in sub-Saharan Africa, where there is a severe HIV epidemic. Thus, accurate recognition and diagnosis of STIs are essential for successful HIV prevention programs in the region. Due to lack of trained personnel and adequate laboratory infrastructure in the region, information regarding the profile of STIs relies essentially on self-reported or physician-diagnosed symptoms. The main objective of the study was to assess the effectiveness of the syndromic diagnosis of STIs, which is often used as a proxy for laboratory diagnosis of STIs in sub-Saharan Africa and other resource-limited settings. The study builds on previously collected data from a community-based survey in Northern Tanzania. We found no significant agreements between patient-reported STIs symptoms and laboratory-confirmed STIs tests. The reported STIs symptoms had high specificity (range = 85-99%) and poor sensitivity (range = 2-17%). Knowledge gained from our study will have significant public health implications, and can help improve the syndromic diagnosis of STIs.

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