Narisorn Kongruttanachok, Yvon E Cayre, Hans Knecht, Sabine Mai
{"title":"单核霍奇金细胞与多核reed-sternberg细胞的快速分离。","authors":"Narisorn Kongruttanachok, Yvon E Cayre, Hans Knecht, Sabine Mai","doi":"10.1532/LH96.12023","DOIUrl":null,"url":null,"abstract":"<p><p>We describe a method to isolate small mononucleated Hodgkin (H) cells from multinucleated Reed Sternberg (RS) cells of Hodgkin lymphoma using the ScreenCell filter device. This filtration-based approach lends itself to future clinical applications in that it enables the separation of H and RS cells from lymph node biopsies, bone marrow aspirates, pleural effusions, and blood, including the isolation of monoclonal Hodgkin precursor cells from the blood. </p>","PeriodicalId":85078,"journal":{"name":"Laboratory hematology : official publication of the International Society for Laboratory Hematology","volume":"20 1","pages":"2-6"},"PeriodicalIF":0.0000,"publicationDate":"2014-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Rapid separation of mononuclear hodgkin from multinuclear reed-sternberg cells.\",\"authors\":\"Narisorn Kongruttanachok, Yvon E Cayre, Hans Knecht, Sabine Mai\",\"doi\":\"10.1532/LH96.12023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We describe a method to isolate small mononucleated Hodgkin (H) cells from multinucleated Reed Sternberg (RS) cells of Hodgkin lymphoma using the ScreenCell filter device. This filtration-based approach lends itself to future clinical applications in that it enables the separation of H and RS cells from lymph node biopsies, bone marrow aspirates, pleural effusions, and blood, including the isolation of monoclonal Hodgkin precursor cells from the blood. </p>\",\"PeriodicalId\":85078,\"journal\":{\"name\":\"Laboratory hematology : official publication of the International Society for Laboratory Hematology\",\"volume\":\"20 1\",\"pages\":\"2-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Laboratory hematology : official publication of the International Society for Laboratory Hematology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1532/LH96.12023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laboratory hematology : official publication of the International Society for Laboratory Hematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1532/LH96.12023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Rapid separation of mononuclear hodgkin from multinuclear reed-sternberg cells.
We describe a method to isolate small mononucleated Hodgkin (H) cells from multinucleated Reed Sternberg (RS) cells of Hodgkin lymphoma using the ScreenCell filter device. This filtration-based approach lends itself to future clinical applications in that it enables the separation of H and RS cells from lymph node biopsies, bone marrow aspirates, pleural effusions, and blood, including the isolation of monoclonal Hodgkin precursor cells from the blood.