新型延长周期左炔诺孕酮-乙炔雌二醇口服避孕药。

Rachel A Bonnema, Abby L Spencer
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引用次数: 0

摘要

有效的避孕咨询需要了解女性的偏好和病史,以及每种避孕方法的风险、益处、副作用和禁忌症。使用各种给药方法的激素避孕药非常有效,本综述重点介绍新型的延长周期左炔诺孕酮-炔雌醇避孕药。长周期 OCP 的独特之处在于一年内减少或无撤退性出血,但医疗服务提供者需要就最初增加的突破性出血仔细向妇女提供咨询。延长周期的 OCPs 可能对以下人群特别有益:患有合并症的女性,她们会从减少撤退性出血中获益;由于荷尔蒙撤退症状加重而希望避免每月来月经的女性;或者仅仅是不希望每月来月经的女性。研究发现,所有延长周期的 OCPs 的相关风险与传统的 OCPs 相似,因此有关风险和副作用的咨询与任何复合激素避孕药的咨询类似。较新的延长周期方案缩短或取消了无激素间隔期,将月经次数减少到每年四次,或完全取消月经。这可以降低常见月经症状、子宫内膜异位症或严重痛经的风险,因为它可以提供潜在的更大卵巢抑制作用,防止内源性雌二醇的产生,同时还能提供高效、快速可逆和安全的避孕效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The new extended-cycle levonorgestrel-ethinyl estradiol oral contraceptives.

Effective contraceptive counseling requires an understanding of a woman's preferences and medical history as well as the risks, benefits, side effects, and contraindications of each contraceptive method. Hormonal contraceptives using a variety of delivery methods are highly effective and this review highlights the new extended-cycle levonorgestrel-ethinyl estradiol contraceptives. Extended-cycle OCPs are unique in offering fewer or no withdrawal bleeds over the course of one year but providers need to carefully counsel women regarding the initial increased breakthrough bleeding. Extended-cycle OCPs may be of particular benefit in women with medical comorbidities who would benefit from less withdrawal bleeds, those desiring to avoid monthly menses due to increased hormonal withdrawal symptoms, or simply women who don't desire a monthly period. The risks associated with all extended-cycle OCPs have been found to be similar to those of traditional OCPs therefore counseling on the risks and side effects is comparable to that of any combined hormonal contraceptives. Newer extended-cycle regimens shorten or eliminate the hormone-free interval, decrease frequency of menses to four times per year or eliminate menses altogether. This can reduce the risk of common menstrual symptoms, endometriosis, or severe dysmenorrhea by offering potentially greater ovarian suppression and preventing endogenous estradiol production while still providing highly effective, rapidly reversible, and safe contraception.

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来源期刊
自引率
0.00%
发文量
0
审稿时长
8 weeks
期刊介绍: Clinical Medicine Insights: Reproductive Health is a peer reviewed; open access journal, which covers all aspects of Reproduction: Gynecology, Obstetrics, and Infertility, spanning both male and female issues, from the physical to the psychological and the social, including: sex, contraception, pregnancy, childbirth, and related topics such as social and emotional impacts. It welcomes original research and review articles from across the health sciences. Clinical subjects include fertility and sterility, infertility and assisted reproduction, IVF, fertility preservation despite gonadotoxic chemo- and/or radiotherapy, pregnancy problems, PPD, infections and disease, surgery, diagnosis, menopause, HRT, pelvic floor problems, reproductive cancers and environmental impacts on reproduction, although this list is by no means exhaustive Subjects covered include, but are not limited to: • fertility and sterility, • infertility and ART, • ART/IVF, • fertility preservation despite gonadotoxic chemo- and/or radiotherapy, • pregnancy problems, • Postpartum depression • Infections and disease, • Gyn/Ob surgery, • diagnosis, • Contraception • Premenstrual tension • Gynecologic Oncology • reproductive cancers • environmental impacts on reproduction, • Obstetrics/Gynaecology • Women''s Health • menopause, • HRT, • pelvic floor problems, • Paediatric and adolescent gynaecology • PID
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