[古巴首次报道布鲁氏菌病引起的感染性心内膜炎]。

Q4 Medicine
Revista Cubana de Medicina Tropical Pub Date : 2012-01-01
Gloria Sofia García González, Iraida Maria Saborido Pérez, Lázaro Ramírez Lana, Isabel Ponce de León Avila
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引用次数: 0

摘要

导读:目前对布鲁氏菌病的临床表现研究较少,对布鲁氏菌病的症状和可能的并发症研究也不深入。目的:报道古巴首例由布鲁氏菌病引起的感染性心内膜炎。方法:2009年12月,一名57岁的白人男性农民从维登特斯市转至卡马圭省“Manuel ascce Domenech”省级医院。由于患者出现发热、全身不适、疲劳、肌肉和关节痛、关节炎、明显虚弱、厌食、神经系统症状、出汗和强烈胸痛,推定诊断为布鲁氏菌引起的感染性心内膜炎和中度主动脉衰竭。在他以前住院期间,他在接受布鲁氏菌病缓慢血清学等补充检查后接受了抗菌素治疗;但是,由于没有特定的试剂,因此直到2010年1月才进行这些测试。该病例的流行病学史包括他与牛和猪的直接接触,以及他的工作类型在他的手和脚上造成的伤口和轻微创伤。他的农场毗邻另一个农场,那里的牛也感染了布鲁氏菌病。结果:实验室检查阳性,血清学滴度高,虽然无法通过培养分离病原,但血清学证实该疾病和感染性心内膜炎为附加并发症;这需要抗微生物治疗和治疗心脏病的药物。布鲁氏菌病的这些并发症在国际文献中很少被诊断出来,在古巴,这是该疾病的第一次报告。结论:本病例的描述提示诊断感染性心内膜炎可能与布鲁氏菌病的流行病学史有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[First report of infective endocarditis in Cuba as a result of brucellosis].

Introduction: the clinical manifestations of brucellosis have been poorly researched on and the symptoms and possible complications have not been deeply studied either.

Objective: to report a case of infective endocarditis caused by brucellosis for the first time in Cuba.

Methods: a Caucasian male farmer aged 57 years was referred from Vertientes municipality to be admitted at "Manuel Ascunce Domenech" provincial hospital in Camaguey province in December, 2009. He had been presumptively diagnosed with infectious endocarditis caused by Brucella and with moderate aortic failure since he presented with fever, general malaise, fatigue, muscle and joint pains, arthritis, marked asthenia, anorexia, neurological signs, sweating and strong chest pain. In his previous hospitalization, he had been treated with antimicrobials after indication of supplementary tests such as slow serology for brucellosis; however, specific reagents were not available,so these tests were not performed until January 2010.The epidemiological history of this case included his direct contact with cows and pigs as well as wounds and minor traumas inflicted on his hands and feet resulting from his type of work. His farm is next to another farm where the cattle is also affected with brucellosis.

Results: the lab tests were positive with high serological titres, and although it was not possible to isolate the etiologic agent through culturing, the disease and the infective endocarditis were serologically confirmed as additional complication; this required antimicrobial treatment and drugs for the heart disease. These complications from brucellosis are barely diagnosed in the international literature, and in Cuba, this is the first report of the disease.

Conclusions: the description of this case is an alert to diagnosis of infective endocarditis that may be associated with epidemiological history of brucellosis.

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来源期刊
Revista Cubana de Medicina Tropical
Revista Cubana de Medicina Tropical Medicine-Infectious Diseases
CiteScore
0.30
自引率
0.00%
发文量
0
期刊介绍: La Revista Cubana de Medicina Tropical tiene la misión de publicar artículos científicos especializados en medicina tropical, microbiología, parasitología, epidemiología y otras especialidades afines. Se distribuye directamente por el editor a los suscriptores en formato impreso (ISSN 0375-0760). Está dirigida a profesionales y técnicos en el campo de la medicina tropical, microbiología, parasitología y epidemiología. Recibe contribuciones en idioma español, inglés y portugués sin distinción en el país de procedencia.
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